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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMF1
All Species:
18.18
Human Site:
T180
Identified Species:
25
UniProt:
P82094
Number Species:
16
Phosphosite Substitution
Charge Score:
0.19
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P82094
NP_009045.2
1093
122842
T180
T
E
G
K
H
E
E
T
V
N
K
E
S
D
M
Chimpanzee
Pan troglodytes
XP_526227
1093
122795
T180
T
E
G
K
H
E
E
T
V
N
K
E
S
D
M
Rhesus Macaque
Macaca mulatta
XP_001088711
1092
122828
V180
E
G
K
H
E
E
T
V
N
K
E
S
D
M
K
Dog
Lupus familis
XP_533766
1089
122761
T180
T
E
G
K
C
E
E
T
I
N
K
E
S
D
M
Cat
Felis silvestris
Mouse
Mus musculus
B9EKI3
1091
121796
E180
K
H
E
E
T
A
G
E
E
S
E
V
K
V
P
Rat
Rattus norvegicus
NP_446123
1093
121882
S180
G
K
R
E
E
T
A
S
E
E
S
E
G
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510334
1106
124384
E180
A
I
P
R
L
K
T
E
M
V
L
E
E
N
I
Chicken
Gallus gallus
O42184
1433
161009
T184
L
A
A
K
E
H
S
T
P
S
Q
F
S
N
L
Frog
Xenopus laevis
Q5PQ23
649
75475
Zebra Danio
Brachydanio rerio
NP_001003522
1136
126986
I180
Q
M
Q
P
E
L
G
I
P
A
S
G
V
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572360
933
103794
I132
S
E
S
S
L
E
L
I
T
A
T
T
A
S
E
Honey Bee
Apis mellifera
XP_394037
1326
150590
S207
N
P
K
I
V
E
Y
S
S
K
E
M
K
D
I
Nematode Worm
Caenorhab. elegans
P02566
1966
225108
S762
S
K
L
V
N
D
G
S
L
S
E
E
M
F
R
Sea Urchin
Strong. purpuratus
XP_785821
1176
131318
S180
I
D
K
E
R
R
T
S
K
S
G
K
K
S
H
Poplar Tree
Populus trichocarpa
XP_002303293
975
109171
C175
K
E
I
S
E
E
G
C
A
E
N
L
D
T
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q0WVL7
956
108335
E156
P
Q
S
Q
I
L
L
E
E
S
S
E
Y
S
L
Baker's Yeast
Sacchar. cerevisiae
P47166
707
81153
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.5
93.1
N.A.
87.2
86.7
N.A.
81.2
21.7
22.6
59.7
N.A.
26.1
23.9
21
37.7
Protein Similarity:
100
99.4
99.1
96.1
N.A.
92.5
92
N.A.
88.3
39.9
37.3
74.6
N.A.
45.8
44.9
36.6
56.8
P-Site Identity:
100
100
6.6
86.6
N.A.
0
6.6
N.A.
6.6
20
0
0
N.A.
13.3
13.3
6.6
0
P-Site Similarity:
100
100
13.3
93.3
N.A.
20
33.3
N.A.
40
46.6
0
0
N.A.
26.6
33.3
60
33.3
Percent
Protein Identity:
25.8
N.A.
N.A.
27.1
21.1
N.A.
Protein Similarity:
47.2
N.A.
N.A.
45.4
39.4
N.A.
P-Site Identity:
13.3
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
20
N.A.
N.A.
33.3
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
6
6
0
0
6
6
0
6
12
0
0
6
6
0
% A
% Cys:
0
0
0
0
6
0
0
6
0
0
0
0
0
0
0
% C
% Asp:
0
6
0
0
0
6
0
0
0
0
0
0
12
24
0
% D
% Glu:
6
30
6
18
30
42
18
18
18
12
24
42
6
0
6
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
6
0
6
0
% F
% Gly:
6
6
18
0
0
0
24
0
0
0
6
6
6
0
0
% G
% His:
0
6
0
6
12
6
0
0
0
0
0
0
0
0
6
% H
% Ile:
6
6
6
6
6
0
0
12
6
0
0
0
0
0
12
% I
% Lys:
12
12
18
24
0
6
0
0
6
12
18
6
18
6
6
% K
% Leu:
6
0
6
0
12
12
12
0
6
0
6
6
0
0
18
% L
% Met:
0
6
0
0
0
0
0
0
6
0
0
6
6
6
18
% M
% Asn:
6
0
0
0
6
0
0
0
6
18
6
0
0
12
0
% N
% Pro:
6
6
6
6
0
0
0
0
12
0
0
0
0
0
12
% P
% Gln:
6
6
6
6
0
0
0
0
0
0
6
0
0
0
0
% Q
% Arg:
0
0
6
6
6
6
0
0
0
0
0
0
0
0
6
% R
% Ser:
12
0
12
12
0
0
6
24
6
30
18
6
24
18
0
% S
% Thr:
18
0
0
0
6
6
18
24
6
0
6
6
0
6
0
% T
% Val:
0
0
0
6
6
0
0
6
12
6
0
6
6
6
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
6
0
0
0
0
0
6
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _