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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CRB1 All Species: 15.76
Human Site: S1389 Identified Species: 31.52
UniProt: P82279 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P82279 NP_957705.1 1406 154183 S1389 S R Q E K E G S R V E M W N L
Chimpanzee Pan troglodytes XP_525009 1406 154097 S1389 S R Q E K E G S R V E M W N L
Rhesus Macaque Macaca mulatta XP_001110912 1406 153778 S1389 S R Q E K E G S R V E M W N L
Dog Lupus familis XP_547379 1466 159959 S1449 S R Q E K E G S R V E M W S M
Cat Felis silvestris
Mouse Mus musculus Q8VHS2 1405 153333 P1388 S G Q E K A G P R V E M W I R
Rat Rattus norvegicus Q07008 2531 270981 T2473 S S S P V D N T P S H Q L Q V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506184 1177 129484 E1170 M D D E P A V E W G D Q E D Y
Chicken Gallus gallus XP_415389 1019 111157 V1012 E M D S V L K V P P E E R L I
Frog Xenopus laevis P21783 2524 275106 D2475 S H Q L Q V P D H P F L T P S
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P10040 2146 233554 P2129 S A Q E Y C N P R L E M D N V
Honey Bee Apis mellifera XP_001121416 2144 234931 P2127 S A Q E F S N P R V E M D N V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus P10079 1064 112055 S1057 K W T R Y E Q S I A P Q P D A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 95.4 77.9 N.A. 76 20.1 N.A. 55.4 30 20.1 N.A. N.A. 25.1 24.4 N.A. 25.1
Protein Similarity: 100 99.2 97.4 85 N.A. 85.4 32.1 N.A. 66.7 44.7 32.3 N.A. N.A. 37.7 38.4 N.A. 37.3
P-Site Identity: 100 100 100 86.6 N.A. 66.6 6.6 N.A. 6.6 6.6 13.3 N.A. N.A. 46.6 53.3 N.A. 13.3
P-Site Similarity: 100 100 100 100 N.A. 66.6 26.6 N.A. 20 13.3 26.6 N.A. N.A. 60 60 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 17 0 0 0 17 0 0 0 9 0 0 0 0 9 % A
% Cys: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 17 0 0 9 0 9 0 0 9 0 17 17 0 % D
% Glu: 9 0 0 67 0 42 0 9 0 0 67 9 9 0 0 % E
% Phe: 0 0 0 0 9 0 0 0 0 0 9 0 0 0 0 % F
% Gly: 0 9 0 0 0 0 42 0 0 9 0 0 0 0 0 % G
% His: 0 9 0 0 0 0 0 0 9 0 9 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 9 0 0 0 0 9 9 % I
% Lys: 9 0 0 0 42 0 9 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 9 0 9 0 0 0 9 0 9 9 9 25 % L
% Met: 9 9 0 0 0 0 0 0 0 0 0 59 0 0 9 % M
% Asn: 0 0 0 0 0 0 25 0 0 0 0 0 0 42 0 % N
% Pro: 0 0 0 9 9 0 9 25 17 17 9 0 9 9 0 % P
% Gln: 0 0 67 0 9 0 9 0 0 0 0 25 0 9 0 % Q
% Arg: 0 34 0 9 0 0 0 0 59 0 0 0 9 0 9 % R
% Ser: 75 9 9 9 0 9 0 42 0 9 0 0 0 9 9 % S
% Thr: 0 0 9 0 0 0 0 9 0 0 0 0 9 0 0 % T
% Val: 0 0 0 0 17 9 9 9 0 50 0 0 0 0 25 % V
% Trp: 0 9 0 0 0 0 0 0 9 0 0 0 42 0 0 % W
% Tyr: 0 0 0 0 17 0 0 0 0 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _