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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MRPS5
All Species:
18.79
Human Site:
Y281
Identified Species:
34.44
UniProt:
P82675
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P82675
NP_114108.1
430
48006
Y281
R
A
V
H
H
L
H
Y
I
E
R
Y
E
D
H
Chimpanzee
Pan troglodytes
XP_515617
430
47962
Y281
R
A
V
H
H
L
H
Y
I
E
R
Y
E
D
H
Rhesus Macaque
Macaca mulatta
XP_001093640
367
41037
L244
R
K
K
S
V
R
V
L
V
A
V
G
N
G
K
Dog
Lupus familis
XP_532953
620
69158
Y471
R
A
V
H
Y
L
H
Y
I
E
R
Y
E
D
H
Cat
Felis silvestris
Mouse
Mus musculus
Q99N87
432
48188
Y283
R
A
I
H
Y
L
H
Y
I
E
R
Y
E
G
H
Rat
Rattus norvegicus
NP_001099975
432
48118
Y283
R
A
I
H
Y
L
H
Y
I
E
R
Y
E
G
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506236
362
41001
K239
R
T
T
I
K
M
K
K
Q
P
R
G
Y
G
L
Chicken
Gallus gallus
XP_415003
407
45670
F258
K
A
I
R
S
L
H
F
I
E
L
Y
Q
N
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001070064
397
44120
Y255
Y
I
E
R
Y
N
D
Y
T
I
Y
H
D
I
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001036652
407
45967
K278
R
A
I
Q
T
I
C
K
V
I
G
I
K
D
L
Honey Bee
Apis mellifera
XP_394577
436
49619
G290
D
L
F
A
K
I
E
G
S
N
N
V
S
S
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788848
355
40528
R232
E
V
T
R
I
R
M
R
K
Q
N
K
G
Y
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P33759
307
34865
G184
G
M
V
G
L
G
E
G
K
S
R
E
E
M
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
75.1
59.1
N.A.
80
81
N.A.
48.8
61.4
N.A.
56
N.A.
35.3
36.2
N.A.
43.4
Protein Similarity:
100
99.7
80.4
64.6
N.A.
87.2
88.1
N.A.
61.8
78.3
N.A.
74.4
N.A.
53
53.6
N.A.
56.9
P-Site Identity:
100
100
6.6
93.3
N.A.
80
80
N.A.
13.3
46.6
N.A.
6.6
N.A.
20
0
N.A.
0
P-Site Similarity:
100
100
13.3
100
N.A.
93.3
93.3
N.A.
20
80
N.A.
26.6
N.A.
46.6
6.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
33.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
54
0
8
0
0
0
0
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
8
0
0
0
0
0
8
31
0
% D
% Glu:
8
0
8
0
0
0
16
0
0
47
0
8
47
0
8
% E
% Phe:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
8
0
8
0
16
0
0
8
16
8
31
8
% G
% His:
0
0
0
39
16
0
47
0
0
0
0
8
0
0
47
% H
% Ile:
0
8
31
8
8
16
0
0
47
16
0
8
0
8
8
% I
% Lys:
8
8
8
0
16
0
8
16
16
0
0
8
8
0
8
% K
% Leu:
0
8
0
0
8
47
0
8
0
0
8
0
0
0
16
% L
% Met:
0
8
0
0
0
8
8
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
8
16
0
8
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
0
0
0
8
8
0
0
8
0
0
% Q
% Arg:
62
0
0
24
0
16
0
8
0
0
54
0
0
0
0
% R
% Ser:
0
0
0
8
8
0
0
0
8
8
0
0
8
8
8
% S
% Thr:
0
8
16
0
8
0
0
0
8
0
0
0
0
0
0
% T
% Val:
0
8
31
0
8
0
8
0
16
0
8
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
31
0
0
47
0
0
8
47
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _