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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HTRA3
All Species:
12.73
Human Site:
S134
Identified Species:
28
UniProt:
P83110
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P83110
NP_444272.1
453
48608
S134
P
L
G
L
H
Q
L
S
S
P
R
Y
K
F
N
Chimpanzee
Pan troglodytes
XP_508084
598
64926
N281
G
Q
G
Q
E
D
P
N
S
L
R
H
K
Y
N
Rhesus Macaque
Macaca mulatta
XP_001103628
481
51453
N164
G
Q
G
Q
E
D
P
N
S
L
R
H
K
Y
N
Dog
Lupus familis
XP_535044
364
39543
V85
F
S
K
R
E
V
P
V
A
S
G
S
G
F
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9D236
459
49131
T140
P
S
G
L
H
Q
L
T
S
P
R
Y
K
F
N
Rat
Rattus norvegicus
XP_341238
459
49239
T140
P
S
G
L
H
Q
L
T
S
P
R
Y
K
F
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420813
466
50374
S147
E
S
G
H
L
Q
S
S
S
P
R
Y
K
F
N
Frog
Xenopus laevis
NP_001088796
457
48812
D140
Q
Q
G
Q
K
D
P
D
S
P
R
Y
K
Y
N
Zebra Danio
Brachydanio rerio
NP_001003502
489
53108
N146
S
S
D
P
A
H
L
N
S
P
R
Y
K
F
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VFJ3
422
45981
C113
I
A
D
V
V
A
G
C
A
D
S
V
V
Y
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q3E6S8
459
49256
S140
S
D
S
S
S
K
P
S
N
G
Y
L
G
R
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
44.3
57.5
49.8
N.A.
91.7
91.2
N.A.
N.A.
77.4
56.8
63.3
N.A.
37
N.A.
N.A.
N.A.
Protein Similarity:
100
58.1
72.3
64.2
N.A.
95.4
94.9
N.A.
N.A.
85.1
71.9
75
N.A.
56.7
N.A.
N.A.
N.A.
P-Site Identity:
100
33.3
33.3
6.6
N.A.
86.6
86.6
N.A.
N.A.
66.6
46.6
53.3
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
53.3
53.3
13.3
N.A.
93.3
93.3
N.A.
N.A.
66.6
53.3
60
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
10
10
0
0
19
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
10
19
0
0
28
0
10
0
10
0
0
0
0
10
% D
% Glu:
10
0
0
0
28
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
0
55
0
% F
% Gly:
19
0
64
0
0
0
10
0
0
10
10
0
19
0
0
% G
% His:
0
0
0
10
28
10
0
0
0
0
0
19
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
19
% I
% Lys:
0
0
10
0
10
10
0
0
0
0
0
0
73
0
0
% K
% Leu:
0
10
0
28
10
0
37
0
0
19
0
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
28
10
0
0
0
0
0
73
% N
% Pro:
28
0
0
10
0
0
46
0
0
55
0
0
0
0
0
% P
% Gln:
10
28
0
28
0
37
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
10
0
0
0
0
0
0
73
0
0
10
0
% R
% Ser:
19
46
10
10
10
0
10
28
73
10
10
10
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
19
0
0
0
0
0
0
0
% T
% Val:
0
0
0
10
10
10
0
10
0
0
0
10
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
55
0
37
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _