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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HTRA3
All Species:
26.06
Human Site:
S214
Identified Species:
57.33
UniProt:
P83110
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P83110
NP_444272.1
453
48608
S214
V
Q
L
Q
N
G
D
S
Y
E
A
T
I
K
D
Chimpanzee
Pan troglodytes
XP_508084
598
64926
T355
V
E
L
K
N
G
A
T
Y
E
A
K
I
K
D
Rhesus Macaque
Macaca mulatta
XP_001103628
481
51453
T238
V
E
L
K
N
G
A
T
Y
E
A
K
I
K
D
Dog
Lupus familis
XP_535044
364
39543
E143
A
L
I
K
I
D
H
E
G
R
L
P
V
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9D236
459
49131
A220
V
Q
L
Q
N
G
D
A
Y
E
A
T
I
Q
D
Rat
Rattus norvegicus
XP_341238
459
49239
A220
V
Q
L
Q
N
G
D
A
Y
E
A
T
I
Q
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420813
466
50374
T227
V
Q
L
Q
N
G
D
T
Y
E
A
T
I
R
D
Frog
Xenopus laevis
NP_001088796
457
48812
T214
V
E
R
S
D
G
S
T
Y
D
A
Q
I
I
D
Zebra Danio
Brachydanio rerio
NP_001003502
489
53108
T226
V
Q
L
H
D
G
Q
T
Y
E
A
S
I
R
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VFJ3
422
45981
T176
V
R
L
S
D
G
R
T
F
P
A
T
I
E
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q3E6S8
459
49256
T220
V
T
L
Q
D
G
R
T
F
E
G
V
V
V
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
44.3
57.5
49.8
N.A.
91.7
91.2
N.A.
N.A.
77.4
56.8
63.3
N.A.
37
N.A.
N.A.
N.A.
Protein Similarity:
100
58.1
72.3
64.2
N.A.
95.4
94.9
N.A.
N.A.
85.1
71.9
75
N.A.
56.7
N.A.
N.A.
N.A.
P-Site Identity:
100
66.6
66.6
0
N.A.
86.6
86.6
N.A.
N.A.
86.6
40
60
N.A.
46.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
86.6
86.6
20
N.A.
100
100
N.A.
N.A.
100
66.6
86.6
N.A.
80
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
19
19
0
0
82
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
37
10
37
0
0
10
0
0
0
0
82
% D
% Glu:
0
28
0
0
0
0
0
10
0
73
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
19
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
91
0
0
10
0
10
0
0
0
0
% G
% His:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
10
0
0
0
0
0
0
0
82
10
0
% I
% Lys:
0
0
0
28
0
0
0
0
0
0
0
19
0
28
0
% K
% Leu:
0
10
82
0
0
0
0
0
0
0
10
0
0
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
55
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% P
% Gln:
0
46
0
46
0
0
10
0
0
0
0
10
0
19
0
% Q
% Arg:
0
10
10
0
0
0
19
0
0
10
0
0
0
19
0
% R
% Ser:
0
0
0
19
0
0
10
10
0
0
0
10
0
0
0
% S
% Thr:
0
10
0
0
0
0
0
64
0
0
0
46
0
0
0
% T
% Val:
91
0
0
0
0
0
0
0
0
0
0
10
19
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
73
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _