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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HTRA3
All Species:
20
Human Site:
S36
Identified Species:
44
UniProt:
P83110
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P83110
NP_444272.1
453
48608
S36
C
D
V
S
R
C
P
S
P
R
C
P
G
G
Y
Chimpanzee
Pan troglodytes
XP_508084
598
64926
S183
P
A
V
P
A
R
P
S
P
S
L
P
G
G
P
Rhesus Macaque
Macaca mulatta
XP_001103628
481
51453
C66
A
R
D
A
C
G
C
C
E
V
C
G
A
P
E
Dog
Lupus familis
XP_535044
364
39543
Cat
Felis silvestris
Mouse
Mus musculus
Q9D236
459
49131
S42
C
D
V
S
R
C
P
S
P
R
C
P
G
G
Y
Rat
Rattus norvegicus
XP_341238
459
49239
S42
C
D
V
S
R
C
P
S
P
R
C
P
G
G
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420813
466
50374
S41
C
D
V
S
K
C
P
S
P
S
C
P
S
G
Y
Frog
Xenopus laevis
NP_001088796
457
48812
S42
P
A
P
T
N
C
Q
S
G
E
T
A
L
R
C
Zebra Danio
Brachydanio rerio
NP_001003502
489
53108
S37
C
D
V
S
K
C
P
S
P
S
C
P
S
G
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VFJ3
422
45981
C16
L
E
V
I
F
K
R
C
I
A
S
P
V
L
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q3E6S8
459
49256
R44
R
A
V
S
S
S
K
R
S
E
L
I
R
I
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
44.3
57.5
49.8
N.A.
91.7
91.2
N.A.
N.A.
77.4
56.8
63.3
N.A.
37
N.A.
N.A.
N.A.
Protein Similarity:
100
58.1
72.3
64.2
N.A.
95.4
94.9
N.A.
N.A.
85.1
71.9
75
N.A.
56.7
N.A.
N.A.
N.A.
P-Site Identity:
100
46.6
6.6
0
N.A.
100
100
N.A.
N.A.
80
13.3
80
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
46.6
13.3
0
N.A.
100
100
N.A.
N.A.
86.6
20
86.6
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
28
0
10
10
0
0
0
0
10
0
10
10
0
0
% A
% Cys:
46
0
0
0
10
55
10
19
0
0
55
0
0
0
10
% C
% Asp:
0
46
10
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
10
0
0
0
0
0
0
10
19
0
0
0
0
10
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
0
0
10
0
0
10
37
55
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
0
10
0
0
0
0
10
0
0
10
0
10
10
% I
% Lys:
0
0
0
0
19
10
10
0
0
0
0
0
0
0
0
% K
% Leu:
10
0
0
0
0
0
0
0
0
0
19
0
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
19
0
10
10
0
0
55
0
55
0
0
64
0
10
10
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
10
10
0
0
28
10
10
10
0
28
0
0
10
10
0
% R
% Ser:
0
0
0
55
10
10
0
64
10
28
10
0
19
0
0
% S
% Thr:
0
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% T
% Val:
0
0
73
0
0
0
0
0
0
10
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
46
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _