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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HTRA3
All Species:
29.39
Human Site:
T363
Identified Species:
64.67
UniProt:
P83110
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P83110
NP_444272.1
453
48608
T363
F
I
G
I
R
M
R
T
I
T
P
S
L
V
D
Chimpanzee
Pan troglodytes
XP_508084
598
64926
S507
Y
I
G
I
R
M
M
S
L
T
S
S
K
A
K
Rhesus Macaque
Macaca mulatta
XP_001103628
481
51453
S390
Y
I
G
I
R
M
M
S
L
T
S
S
K
A
K
Dog
Lupus familis
XP_535044
364
39543
K283
S
S
K
A
K
E
L
K
D
H
H
R
D
F
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9D236
459
49131
T369
F
I
G
I
R
M
R
T
I
T
P
S
L
V
E
Rat
Rattus norvegicus
XP_341238
459
49239
T369
F
I
G
I
R
M
R
T
I
T
P
S
L
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420813
466
50374
T376
F
I
G
I
R
M
L
T
I
T
P
A
L
V
E
Frog
Xenopus laevis
NP_001088796
457
48812
S366
Y
L
G
I
R
M
M
S
L
S
Q
G
K
L
K
Zebra Danio
Brachydanio rerio
NP_001003502
489
53108
T398
F
I
G
I
K
M
V
T
L
T
E
N
L
V
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VFJ3
422
45981
T331
Y
M
G
I
T
M
L
T
L
T
P
D
I
L
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q3E6S8
459
49256
E369
W
I
G
L
K
M
V
E
L
N
N
L
I
V
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
44.3
57.5
49.8
N.A.
91.7
91.2
N.A.
N.A.
77.4
56.8
63.3
N.A.
37
N.A.
N.A.
N.A.
Protein Similarity:
100
58.1
72.3
64.2
N.A.
95.4
94.9
N.A.
N.A.
85.1
71.9
75
N.A.
56.7
N.A.
N.A.
N.A.
P-Site Identity:
100
46.6
46.6
0
N.A.
93.3
93.3
N.A.
N.A.
80
26.6
60
N.A.
40
N.A.
N.A.
N.A.
P-Site Similarity:
100
66.6
66.6
6.6
N.A.
100
100
N.A.
N.A.
93.3
66.6
80
N.A.
73.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
0
0
0
10
0
19
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
0
0
10
10
0
10
% D
% Glu:
0
0
0
0
0
10
0
10
0
0
10
0
0
0
28
% E
% Phe:
46
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% F
% Gly:
0
0
91
0
0
0
0
0
0
0
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
10
% H
% Ile:
0
73
0
82
0
0
0
0
37
0
0
0
19
0
0
% I
% Lys:
0
0
10
0
28
0
0
10
0
0
0
0
28
0
28
% K
% Leu:
0
10
0
10
0
0
28
0
55
0
0
10
46
19
0
% L
% Met:
0
10
0
0
0
91
28
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
10
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
46
0
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Q
% Arg:
0
0
0
0
64
0
28
0
0
0
0
10
0
0
0
% R
% Ser:
10
10
0
0
0
0
0
28
0
10
19
46
0
0
0
% S
% Thr:
0
0
0
0
10
0
0
55
0
73
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
19
0
0
0
0
0
0
55
0
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
37
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _