KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HTRA3
All Species:
21.52
Human Site:
Y387
Identified Species:
47.33
UniProt:
P83110
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P83110
NP_444272.1
453
48608
Y387
P
E
V
S
S
G
I
Y
V
Q
E
V
A
P
N
Chimpanzee
Pan troglodytes
XP_508084
598
64926
Y531
P
D
V
I
S
G
A
Y
I
I
E
V
I
P
D
Rhesus Macaque
Macaca mulatta
XP_001103628
481
51453
Y414
P
D
V
I
S
G
A
Y
I
I
E
V
I
P
D
Dog
Lupus familis
XP_535044
364
39543
A307
E
V
I
P
D
T
P
A
E
A
G
G
L
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9D236
459
49131
Y393
P
A
V
S
S
G
I
Y
V
Q
E
V
V
P
N
Rat
Rattus norvegicus
XP_341238
459
49239
Y393
P
A
V
S
S
G
I
Y
V
Q
E
V
V
P
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420813
466
50374
Y400
P
D
V
R
S
G
I
Y
V
H
E
V
V
P
N
Frog
Xenopus laevis
NP_001088796
457
48812
Y390
P
E
N
T
S
G
A
Y
I
V
E
V
L
P
D
Zebra Danio
Brachydanio rerio
NP_001003502
489
53108
L422
P
D
I
G
S
G
I
L
V
H
E
V
I
A
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VFJ3
422
45981
V355
P
S
N
L
T
H
G
V
L
V
W
K
V
I
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q3E6S8
459
49256
L393
P
D
V
E
R
G
V
L
V
P
T
V
I
P
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
44.3
57.5
49.8
N.A.
91.7
91.2
N.A.
N.A.
77.4
56.8
63.3
N.A.
37
N.A.
N.A.
N.A.
Protein Similarity:
100
58.1
72.3
64.2
N.A.
95.4
94.9
N.A.
N.A.
85.1
71.9
75
N.A.
56.7
N.A.
N.A.
N.A.
P-Site Identity:
100
53.3
53.3
0
N.A.
86.6
86.6
N.A.
N.A.
73.3
53.3
46.6
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
73.3
73.3
6.6
N.A.
86.6
86.6
N.A.
N.A.
80
73.3
66.6
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
0
0
0
0
28
10
0
10
0
0
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
46
0
0
10
0
0
0
0
0
0
0
0
0
37
% D
% Glu:
10
19
0
10
0
0
0
0
10
0
73
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
82
10
0
0
0
10
10
0
0
10
% G
% His:
0
0
0
0
0
10
0
0
0
19
0
0
0
0
0
% H
% Ile:
0
0
19
19
0
0
46
0
28
19
0
0
37
10
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% K
% Leu:
0
0
0
10
0
0
0
19
10
0
0
0
19
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
19
0
0
0
0
0
0
0
0
0
0
0
37
% N
% Pro:
91
0
0
10
0
0
10
0
0
10
0
0
0
73
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
28
0
0
0
0
0
% Q
% Arg:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
0
28
73
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
10
10
10
0
0
0
0
10
0
0
0
0
% T
% Val:
0
10
64
0
0
0
10
10
55
19
0
82
37
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
64
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _