KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LACTB
All Species:
18.18
Human Site:
S218
Identified Species:
44.44
UniProt:
P83111
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P83111
NP_116246.2
547
60694
S218
R
L
L
I
S
H
L
S
G
I
R
H
Y
E
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001104610
547
60609
S218
R
L
L
I
S
H
L
S
G
I
R
H
Y
E
K
Dog
Lupus familis
XP_544713
464
52180
K141
E
K
D
M
K
K
V
K
E
E
K
A
Y
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9EP89
551
60687
S216
R
L
L
I
S
H
L
S
G
I
R
H
Y
E
K
Rat
Rattus norvegicus
NP_001100303
550
60402
S216
R
L
L
I
S
H
L
S
G
I
R
H
Y
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518282
438
49452
K115
I
K
K
V
K
E
E
K
A
L
K
G
L
R
M
Chicken
Gallus gallus
NP_001025717
520
57986
S176
R
L
L
V
S
H
L
S
G
I
R
H
Y
E
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001018429
536
60352
M209
N
V
T
I
T
P
R
M
L
L
S
H
L
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001041033
407
44448
K84
A
N
L
E
S
F
A
K
C
T
G
D
S
V
M
Sea Urchin
Strong. purpuratus
XP_789736
431
48634
Q108
K
E
A
D
E
D
N
Q
K
D
N
S
N
K
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.1
76.2
N.A.
88
87
N.A.
64.9
66.9
N.A.
51.7
N.A.
N.A.
N.A.
30.1
34
Protein Similarity:
100
N.A.
98.5
79.5
N.A.
92
90.9
N.A.
72
76.5
N.A.
67.2
N.A.
N.A.
N.A.
44.6
49.3
P-Site Identity:
100
N.A.
100
6.6
N.A.
100
100
N.A.
0
93.3
N.A.
13.3
N.A.
N.A.
N.A.
13.3
0
P-Site Similarity:
100
N.A.
100
33.3
N.A.
100
100
N.A.
20
100
N.A.
33.3
N.A.
N.A.
N.A.
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
0
0
10
0
10
0
0
10
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
0
10
10
0
10
0
0
0
10
0
10
0
0
0
% D
% Glu:
10
10
0
10
10
10
10
0
10
10
0
0
0
50
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
50
0
10
10
0
0
10
% G
% His:
0
0
0
0
0
50
0
0
0
0
0
60
0
0
10
% H
% Ile:
10
0
0
50
0
0
0
0
0
50
0
0
0
0
0
% I
% Lys:
10
20
10
0
20
10
0
30
10
0
20
0
0
20
50
% K
% Leu:
0
50
60
0
0
0
50
0
10
20
0
0
20
0
0
% L
% Met:
0
0
0
10
0
0
0
10
0
0
0
0
0
0
20
% M
% Asn:
10
10
0
0
0
0
10
0
0
0
10
0
10
0
0
% N
% Pro:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
50
0
0
0
0
0
10
0
0
0
50
0
0
10
0
% R
% Ser:
0
0
0
0
60
0
0
50
0
0
10
10
10
10
0
% S
% Thr:
0
0
10
0
10
0
0
0
0
10
0
0
0
0
0
% T
% Val:
0
10
0
20
0
0
10
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
60
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _