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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LACTB All Species: 15.76
Human Site: S301 Identified Species: 38.52
UniProt: P83111 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P83111 NP_116246.2 547 60694 S301 L R E K F E N S I E S L R L F
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001104610 547 60609 S301 L R E K F E N S I E S L R L F
Dog Lupus familis XP_544713 464 52180 S219 K F E N S I E S L R L F K N D
Cat Felis silvestris
Mouse Mus musculus Q9EP89 551 60687 S305 L K E K F E N S I E S L R L F
Rat Rattus norvegicus NP_001100303 550 60402 S304 L K E K F E N S I E S L R L F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518282 438 49452 F193 T I E S L R I F K N D P L F F
Chicken Gallus gallus NP_001025717 520 57986 V262 L K E K F E S V I E S L K I F
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001018429 536 60352 V288 L K D N F E S V I Q A L D L F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_001041033 407 44448 E162 A T E K K K S E T H E D P S N
Sea Urchin Strong. purpuratus XP_789736 431 48634 T186 G S K Y V Y T T H G F T L V S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.1 76.2 N.A. 88 87 N.A. 64.9 66.9 N.A. 51.7 N.A. N.A. N.A. 30.1 34
Protein Similarity: 100 N.A. 98.5 79.5 N.A. 92 90.9 N.A. 72 76.5 N.A. 67.2 N.A. N.A. N.A. 44.6 49.3
P-Site Identity: 100 N.A. 100 13.3 N.A. 93.3 93.3 N.A. 13.3 66.6 N.A. 46.6 N.A. N.A. N.A. 13.3 0
P-Site Similarity: 100 N.A. 100 26.6 N.A. 100 100 N.A. 13.3 93.3 N.A. 80 N.A. N.A. N.A. 26.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 0 0 0 0 0 10 10 10 0 10 % D
% Glu: 0 0 80 0 0 60 10 10 0 50 10 0 0 0 0 % E
% Phe: 0 10 0 0 60 0 0 10 0 0 10 10 0 10 70 % F
% Gly: 10 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 10 10 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 10 10 0 60 0 0 0 0 10 0 % I
% Lys: 10 40 10 60 10 10 0 0 10 0 0 0 20 0 0 % K
% Leu: 60 0 0 0 10 0 0 0 10 0 10 60 20 50 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 20 0 0 40 0 0 10 0 0 0 10 10 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 10 10 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % Q
% Arg: 0 20 0 0 0 10 0 0 0 10 0 0 40 0 0 % R
% Ser: 0 10 0 10 10 0 30 50 0 0 50 0 0 10 10 % S
% Thr: 10 10 0 0 0 0 10 10 10 0 0 10 0 0 0 % T
% Val: 0 0 0 0 10 0 0 20 0 0 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 0 10 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _