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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LACTB All Species: 23.33
Human Site: Y393 Identified Species: 57.04
UniProt: P83111 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P83111 NP_116246.2 547 60694 Y393 T P Y V D N S Y K W A G G G F
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001104610 547 60609 Y393 T P Y V D N S Y K W A G G G F
Dog Lupus familis XP_544713 464 52180 A311 V D N S Y K W A G G G F L S T
Cat Felis silvestris
Mouse Mus musculus Q9EP89 551 60687 Y397 T P Y V D N S Y K W A G G G F
Rat Rattus norvegicus NP_001100303 550 60402 Y396 T P Y V D N S Y K W A G G G F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518282 438 49452 Y285 Y K W A G G G Y L S T V G D L
Chicken Gallus gallus NP_001025717 520 57986 Y354 A P Y V D N S Y K W A G G G F
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001018429 536 60352 Y380 C P Y V D N S Y K W A G G G F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_001041033 407 44448 P254 D T K E K I V P G R A S Y Y Q
Sea Urchin Strong. purpuratus XP_789736 431 48634 S278 F G N I M L Y S Y Q Q P A N N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.1 76.2 N.A. 88 87 N.A. 64.9 66.9 N.A. 51.7 N.A. N.A. N.A. 30.1 34
Protein Similarity: 100 N.A. 98.5 79.5 N.A. 92 90.9 N.A. 72 76.5 N.A. 67.2 N.A. N.A. N.A. 44.6 49.3
P-Site Identity: 100 N.A. 100 0 N.A. 100 100 N.A. 13.3 93.3 N.A. 93.3 N.A. N.A. N.A. 6.6 0
P-Site Similarity: 100 N.A. 100 0 N.A. 100 100 N.A. 20 93.3 N.A. 93.3 N.A. N.A. N.A. 6.6 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 10 0 0 0 10 0 0 70 0 10 0 0 % A
% Cys: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 10 0 0 60 0 0 0 0 0 0 0 0 10 0 % D
% Glu: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 10 0 0 0 0 0 0 0 0 0 0 10 0 0 60 % F
% Gly: 0 10 0 0 10 10 10 0 20 10 10 60 70 60 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 0 10 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 10 10 0 10 10 0 0 60 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 10 0 0 10 0 0 0 10 0 10 % L
% Met: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 20 0 0 60 0 0 0 0 0 0 0 10 10 % N
% Pro: 0 60 0 0 0 0 0 10 0 0 0 10 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 10 10 0 0 0 10 % Q
% Arg: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % R
% Ser: 0 0 0 10 0 0 60 10 0 10 0 10 0 10 0 % S
% Thr: 40 10 0 0 0 0 0 0 0 0 10 0 0 0 10 % T
% Val: 10 0 0 60 0 0 10 0 0 0 0 10 0 0 0 % V
% Trp: 0 0 10 0 0 0 10 0 0 60 0 0 0 0 0 % W
% Tyr: 10 0 60 0 10 0 10 70 10 0 0 0 10 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _