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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LACTB All Species: 17.88
Human Site: Y460 Identified Species: 43.7
UniProt: P83111 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P83111 NP_116246.2 547 60694 Y460 S W D K E G K Y A M A W G V V
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001104610 547 60609 Y460 S W D K E G K Y A M A W G V V
Dog Lupus familis XP_544713 464 52180 A378 K E G K Y A M A W G V V E K K
Cat Felis silvestris
Mouse Mus musculus Q9EP89 551 60687 Y464 S W D K E G K Y A M A W G V V
Rat Rattus norvegicus NP_001100303 550 60402 Y463 S W D K E G K Y A M A W G V V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518282 438 49452 V352 Y A M A W G V V E K Q Q R Y G
Chicken Gallus gallus NP_001025717 520 57986 Y421 S W D R D G K Y A M A W A V V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001018429 536 60352 W447 D G Q Y A Q G W L V V E K L Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_001041033 407 44448 L321 R E T I R K F L E K Q V P V D
Sea Urchin Strong. purpuratus XP_789736 431 48634 H345 P T R H F V T H S G G A M G F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.1 76.2 N.A. 88 87 N.A. 64.9 66.9 N.A. 51.7 N.A. N.A. N.A. 30.1 34
Protein Similarity: 100 N.A. 98.5 79.5 N.A. 92 90.9 N.A. 72 76.5 N.A. 67.2 N.A. N.A. N.A. 44.6 49.3
P-Site Identity: 100 N.A. 100 6.6 N.A. 100 100 N.A. 6.6 80 N.A. 0 N.A. N.A. N.A. 6.6 0
P-Site Similarity: 100 N.A. 100 6.6 N.A. 100 100 N.A. 6.6 93.3 N.A. 20 N.A. N.A. N.A. 6.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 10 10 10 0 10 50 0 50 10 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 50 0 10 0 0 0 0 0 0 0 0 0 10 % D
% Glu: 0 20 0 0 40 0 0 0 20 0 0 10 10 0 0 % E
% Phe: 0 0 0 0 10 0 10 0 0 0 0 0 0 0 10 % F
% Gly: 0 10 10 0 0 60 10 0 0 20 10 0 40 10 10 % G
% His: 0 0 0 10 0 0 0 10 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 0 0 50 0 10 50 0 0 20 0 0 10 10 10 % K
% Leu: 0 0 0 0 0 0 0 10 10 0 0 0 0 10 0 % L
% Met: 0 0 10 0 0 0 10 0 0 50 0 0 10 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 10 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % P
% Gln: 0 0 10 0 0 10 0 0 0 0 20 10 0 0 10 % Q
% Arg: 10 0 10 10 10 0 0 0 0 0 0 0 10 0 0 % R
% Ser: 50 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % S
% Thr: 0 10 10 0 0 0 10 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 10 10 10 0 10 20 20 0 60 50 % V
% Trp: 0 50 0 0 10 0 0 10 10 0 0 50 0 0 0 % W
% Tyr: 10 0 0 10 10 0 0 50 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _