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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: COG7 All Species: 35.76
Human Site: S135 Identified Species: 71.52
UniProt: P83436 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P83436 NP_705831.1 770 86344 S135 A D K W S T L S A D I E E T F
Chimpanzee Pan troglodytes XP_510875 770 86371 S135 A D K W S T L S A D I E E T F
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536935 867 97126 S232 A D K W S T L S A D I E E T F
Cat Felis silvestris
Mouse Mus musculus Q3UM29 770 86054 S135 A D K W S T L S A D I E E T F
Rat Rattus norvegicus Q3T1G7 770 86193 S135 A D K W S T L S A D I E E T F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510180 777 87288 S142 A D K W S T L S A D I E E T F
Chicken Gallus gallus XP_001234080 769 86630 S134 A D K W T T L S A D I E E T L
Frog Xenopus laevis NP_001085832 768 86803 S134 A D K W S T L S A D I E E T L
Zebra Danio Brachydanio rerio NP_001070861 767 86211 S134 A D K W S T L S A D I E E T F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VAD6 742 84057 L138 S D G W G N L L A E L E D G F
Honey Bee Apis mellifera XP_394713 733 83501 A132 A D N W S V L A N D V E E I F
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001203886 767 86354 D131 N L P R V L R D V E A V R Q E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 N.A. 82.8 N.A. 92.4 91.4 N.A. 79.4 78.6 75.4 70.5 N.A. 28 36.7 N.A. 44.5
Protein Similarity: 100 99.8 N.A. 86.1 N.A. 95.8 95.1 N.A. 87.1 90.6 88.5 84.8 N.A. 48.1 56.8 N.A. 62
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. 100 86.6 93.3 100 N.A. 40 60 N.A. 0
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 100 93.3 93.3 100 N.A. 66.6 73.3 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 84 0 0 0 0 0 0 9 84 0 9 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 92 0 0 0 0 0 9 0 84 0 0 9 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 17 0 92 84 0 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 75 % F
% Gly: 0 0 9 0 9 0 0 0 0 0 0 0 0 9 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 75 0 0 9 0 % I
% Lys: 0 0 75 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 9 0 0 0 9 92 9 0 0 9 0 0 0 17 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 0 9 0 0 9 0 0 9 0 0 0 0 0 0 % N
% Pro: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % Q
% Arg: 0 0 0 9 0 0 9 0 0 0 0 0 9 0 0 % R
% Ser: 9 0 0 0 75 0 0 75 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 9 75 0 0 0 0 0 0 0 75 0 % T
% Val: 0 0 0 0 9 9 0 0 9 0 9 9 0 0 0 % V
% Trp: 0 0 0 92 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _