Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: COG7 All Species: 19.39
Human Site: T312 Identified Species: 38.79
UniProt: P83436 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P83436 NP_705831.1 770 86344 T312 A G P E Q E L T R L L E F Y D
Chimpanzee Pan troglodytes XP_510875 770 86371 T312 A G P E Q E L T R L L E F Y D
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536935 867 97126 L409 A G P E L E L L K L L E F Y D
Cat Felis silvestris
Mouse Mus musculus Q3UM29 770 86054 T312 A G P E L E L T R L L E F Y D
Rat Rattus norvegicus Q3T1G7 770 86193 T312 A G P E L E L T R L L E F Y D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510180 777 87288 I319 V G P D V K L I K L L E L Y D
Chicken Gallus gallus XP_001234080 769 86630 S311 T G Q E T K L S K L L E L Y D
Frog Xenopus laevis NP_001085832 768 86803 S311 A S E E D K L S T L L E L Y N
Zebra Danio Brachydanio rerio NP_001070861 767 86211 D311 C S G D C R L D V L L E L H Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VAD6 742 84057 K311 A H I L Q L L K T S N E R L E
Honey Bee Apis mellifera XP_394713 733 83501 M309 L K Q H T N A M Q L S L L L E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001203886 767 86354 K305 L Q E T N R E K V L A E W L P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 N.A. 82.8 N.A. 92.4 91.4 N.A. 79.4 78.6 75.4 70.5 N.A. 28 36.7 N.A. 44.5
Protein Similarity: 100 99.8 N.A. 86.1 N.A. 95.8 95.1 N.A. 87.1 90.6 88.5 84.8 N.A. 48.1 56.8 N.A. 62
P-Site Identity: 100 100 N.A. 80 N.A. 93.3 93.3 N.A. 53.3 53.3 46.6 26.6 N.A. 26.6 6.6 N.A. 13.3
P-Site Similarity: 100 100 N.A. 86.6 N.A. 93.3 93.3 N.A. 73.3 73.3 66.6 40 N.A. 33.3 20 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 59 0 0 0 0 0 9 0 0 0 9 0 0 0 0 % A
% Cys: 9 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 17 9 0 0 9 0 0 0 0 0 0 59 % D
% Glu: 0 0 17 59 0 42 9 0 0 0 0 92 0 0 17 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 42 0 0 % F
% Gly: 0 59 9 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 9 0 9 0 0 0 0 0 0 0 0 0 9 0 % H
% Ile: 0 0 9 0 0 0 0 9 0 0 0 0 0 0 0 % I
% Lys: 0 9 0 0 0 25 0 17 25 0 0 0 0 0 0 % K
% Leu: 17 0 0 9 25 9 84 9 0 92 75 9 42 25 0 % L
% Met: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 9 9 0 0 0 0 9 0 0 0 9 % N
% Pro: 0 0 50 0 0 0 0 0 0 0 0 0 0 0 9 % P
% Gln: 0 9 17 0 25 0 0 0 9 0 0 0 0 0 9 % Q
% Arg: 0 0 0 0 0 17 0 0 34 0 0 0 9 0 0 % R
% Ser: 0 17 0 0 0 0 0 17 0 9 9 0 0 0 0 % S
% Thr: 9 0 0 9 17 0 0 34 17 0 0 0 0 0 0 % T
% Val: 9 0 0 0 9 0 0 0 17 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 67 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _