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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COG7
All Species:
21.52
Human Site:
Y358
Identified Species:
43.03
UniProt:
P83436
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P83436
NP_705831.1
770
86344
Y358
V
Y
D
P
Y
K
P
Y
Q
L
K
Y
G
D
M
Chimpanzee
Pan troglodytes
XP_510875
770
86371
Y358
V
Y
D
P
Y
K
P
Y
Q
L
K
Y
G
D
M
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536935
867
97126
Y455
V
Y
G
P
Y
K
P
Y
Q
L
K
Y
G
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q3UM29
770
86054
F358
V
Y
G
P
Y
K
P
F
Q
L
K
Y
G
D
M
Rat
Rattus norvegicus
Q3T1G7
770
86193
Y358
V
Y
G
P
Y
K
P
Y
Q
L
K
Y
G
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510180
777
87288
Y365
V
Y
G
P
Y
K
P
Y
Q
L
Q
Y
G
D
L
Chicken
Gallus gallus
XP_001234080
769
86630
F357
V
Y
H
P
Y
K
P
F
Q
L
K
Y
G
D
L
Frog
Xenopus laevis
NP_001085832
768
86803
F357
V
F
G
P
Y
K
P
F
Q
L
Q
Y
G
D
L
Zebra Danio
Brachydanio rerio
NP_001070861
767
86211
Y357
V
Y
S
P
Y
K
T
Y
Q
I
Q
Y
G
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VAD6
742
84057
E348
S
H
I
T
L
S
E
E
L
H
R
L
L
G
E
Honey Bee
Apis mellifera
XP_394713
733
83501
S346
F
Q
N
S
K
L
L
S
L
A
Q
A
I
Y
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203886
767
86354
L343
A
V
P
M
V
C
E
L
L
A
Q
T
L
S
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
82.8
N.A.
92.4
91.4
N.A.
79.4
78.6
75.4
70.5
N.A.
28
36.7
N.A.
44.5
Protein Similarity:
100
99.8
N.A.
86.1
N.A.
95.8
95.1
N.A.
87.1
90.6
88.5
84.8
N.A.
48.1
56.8
N.A.
62
P-Site Identity:
100
100
N.A.
86.6
N.A.
86.6
86.6
N.A.
80
80
66.6
60
N.A.
0
0
N.A.
0
P-Site Similarity:
100
100
N.A.
93.3
N.A.
93.3
93.3
N.A.
93.3
93.3
93.3
80
N.A.
13.3
13.3
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
0
0
0
17
0
9
0
0
9
% A
% Cys:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
9
% C
% Asp:
0
0
17
0
0
0
0
0
0
0
0
0
0
67
0
% D
% Glu:
0
0
0
0
0
0
17
9
0
0
0
0
0
0
9
% E
% Phe:
9
9
0
0
0
0
0
25
0
0
0
0
0
0
0
% F
% Gly:
0
0
42
0
0
0
0
0
0
0
0
0
75
17
0
% G
% His:
0
9
9
0
0
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
0
0
0
0
9
0
0
9
0
0
% I
% Lys:
0
0
0
0
9
75
0
0
0
0
50
0
0
0
0
% K
% Leu:
0
0
0
0
9
9
9
9
25
67
0
9
17
0
50
% L
% Met:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
25
% M
% Asn:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
9
75
0
0
67
0
0
0
0
0
0
0
0
% P
% Gln:
0
9
0
0
0
0
0
0
75
0
42
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% R
% Ser:
9
0
9
9
0
9
0
9
0
0
0
0
0
9
0
% S
% Thr:
0
0
0
9
0
0
9
0
0
0
0
9
0
0
0
% T
% Val:
75
9
0
0
9
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
67
0
0
75
0
0
50
0
0
0
75
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _