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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COG7
All Species:
27.27
Human Site:
Y500
Identified Species:
54.55
UniProt:
P83436
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P83436
NP_705831.1
770
86344
Y500
I
L
S
T
A
G
K
Y
L
S
D
S
C
S
P
Chimpanzee
Pan troglodytes
XP_510875
770
86371
Y500
I
L
S
T
A
G
K
Y
L
S
D
S
C
S
P
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536935
867
97126
Y597
I
L
S
T
A
G
K
Y
L
S
D
S
Y
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q3UM29
770
86054
Y500
I
L
S
T
A
G
K
Y
L
S
D
S
Y
S
P
Rat
Rattus norvegicus
Q3T1G7
770
86193
Y500
I
L
S
T
A
G
K
Y
L
S
D
S
Y
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510180
777
87288
Y507
I
L
T
T
A
G
K
Y
L
S
D
S
Y
S
P
Chicken
Gallus gallus
XP_001234080
769
86630
Y499
I
L
S
T
A
G
K
Y
L
S
D
S
Y
S
P
Frog
Xenopus laevis
NP_001085832
768
86803
K498
R
F
L
S
I
A
G
K
H
L
S
D
S
Y
S
Zebra Danio
Brachydanio rerio
NP_001070861
767
86211
G497
N
K
I
L
G
R
A
G
R
F
L
W
E
G
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VAD6
742
84057
Q482
L
Q
C
L
A
D
F
Q
V
Q
L
H
Q
F
E
Honey Bee
Apis mellifera
XP_394713
733
83501
L480
I
Q
Q
F
E
K
S
L
M
I
D
I
I
E
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203886
767
86354
T490
K
F
D
R
S
L
E
T
L
R
S
A
C
G
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
82.8
N.A.
92.4
91.4
N.A.
79.4
78.6
75.4
70.5
N.A.
28
36.7
N.A.
44.5
Protein Similarity:
100
99.8
N.A.
86.1
N.A.
95.8
95.1
N.A.
87.1
90.6
88.5
84.8
N.A.
48.1
56.8
N.A.
62
P-Site Identity:
100
100
N.A.
93.3
N.A.
93.3
93.3
N.A.
86.6
93.3
0
0
N.A.
6.6
13.3
N.A.
13.3
P-Site Similarity:
100
100
N.A.
93.3
N.A.
93.3
93.3
N.A.
93.3
93.3
6.6
0
N.A.
20
20
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
67
9
9
0
0
0
0
9
0
0
9
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
0
0
25
0
0
% C
% Asp:
0
0
9
0
0
9
0
0
0
0
67
9
0
0
0
% D
% Glu:
0
0
0
0
9
0
9
0
0
0
0
0
9
9
9
% E
% Phe:
0
17
0
9
0
0
9
0
0
9
0
0
0
9
9
% F
% Gly:
0
0
0
0
9
59
9
9
0
0
0
0
0
17
0
% G
% His:
0
0
0
0
0
0
0
0
9
0
0
9
0
0
0
% H
% Ile:
67
0
9
0
9
0
0
0
0
9
0
9
9
0
0
% I
% Lys:
9
9
0
0
0
9
59
9
0
0
0
0
0
0
0
% K
% Leu:
9
59
9
17
0
9
0
9
67
9
17
0
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
59
% P
% Gln:
0
17
9
0
0
0
0
9
0
9
0
0
9
0
0
% Q
% Arg:
9
0
0
9
0
9
0
0
9
9
0
0
0
0
0
% R
% Ser:
0
0
50
9
9
0
9
0
0
59
17
59
9
59
9
% S
% Thr:
0
0
9
59
0
0
0
9
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
59
0
0
0
0
42
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _