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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HPCA
All Species:
40.91
Human Site:
S143
Identified Species:
69.23
UniProt:
P84074
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P84074
NP_002134.2
193
22427
S143
M
K
M
P
E
D
E
S
T
P
E
K
R
T
E
Chimpanzee
Pan troglodytes
XP_001155509
344
38260
S294
M
K
M
P
E
D
E
S
T
P
E
K
R
T
E
Rhesus Macaque
Macaca mulatta
XP_001098851
408
45214
S358
M
K
M
P
E
D
E
S
T
P
E
K
R
T
E
Dog
Lupus familis
XP_852217
329
37131
S279
M
K
M
P
E
D
E
S
T
P
E
K
R
T
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGZ1
191
22197
N141
T
V
I
M
M
R
M
N
Q
D
G
L
T
P
Q
Rat
Rattus norvegicus
P84076
193
22409
S143
M
K
M
P
E
D
E
S
T
P
E
K
R
T
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P42324
193
22251
S143
M
K
M
P
E
D
E
S
T
P
E
K
R
T
D
Frog
Xenopus laevis
Q6DCM9
193
22267
S143
M
K
M
P
E
D
E
S
T
P
E
K
R
T
D
Zebra Danio
Brachydanio rerio
A9JTH1
193
22206
S143
M
K
M
P
E
D
E
S
T
P
E
K
R
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P42325
190
21875
D141
S
V
M
K
M
P
E
D
E
S
T
P
E
K
R
Honey Bee
Apis mellifera
XP_392256
192
21952
S143
M
K
M
P
E
D
E
S
T
P
E
K
R
T
D
Nematode Worm
Caenorhab. elegans
P36608
191
22003
E142
S
V
Q
L
P
E
E
E
N
T
P
E
K
R
V
Sea Urchin
Strong. purpuratus
XP_783112
194
22350
S143
M
K
M
P
E
D
E
S
T
P
E
K
R
T
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06389
190
21992
D141
S
M
V
T
L
N
E
D
E
A
T
P
E
M
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
56
47.2
54.7
N.A.
66.8
100
N.A.
N.A.
93.2
92.2
87
N.A.
83.4
83.9
56.9
85.5
Protein Similarity:
100
56
47.2
56.8
N.A.
82.3
100
N.A.
N.A.
96.8
96.3
94.8
N.A.
91.1
92.7
73
91.7
P-Site Identity:
100
100
100
93.3
N.A.
0
100
N.A.
N.A.
93.3
93.3
100
N.A.
13.3
93.3
6.6
93.3
P-Site Similarity:
100
100
100
100
N.A.
20
100
N.A.
N.A.
100
100
100
N.A.
13.3
100
26.6
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
48.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
68.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
72
0
15
0
8
0
0
0
0
36
% D
% Glu:
0
0
0
0
72
8
93
8
15
0
72
8
15
0
36
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
72
0
8
0
0
0
0
0
0
0
72
8
8
0
% K
% Leu:
0
0
0
8
8
0
0
0
0
0
0
8
0
0
0
% L
% Met:
72
8
79
8
15
0
8
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
0
8
0
8
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
72
8
8
0
0
0
72
8
15
0
8
0
% P
% Gln:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
8
% Q
% Arg:
0
0
0
0
0
8
0
0
0
0
0
0
72
8
15
% R
% Ser:
22
0
0
0
0
0
0
72
0
8
0
0
0
0
0
% S
% Thr:
8
0
0
8
0
0
0
0
72
8
15
0
8
72
0
% T
% Val:
0
22
8
0
0
0
0
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _