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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARF5 All Species: 65.13
Human Site: S174 Identified Species: 89.55
UniProt: P84085 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P84085 NP_001653.1 180 20530 S174 Y D G L D W L S H E L S K R _
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001103974 180 20437 S174 Y E G L D W L S N E L S K R _
Dog Lupus familis XP_858890 164 18600 S158 Y D G L D W L S H E L S K R _
Cat Felis silvestris
Mouse Mus musculus Q8BGX0 574 63913 S562 Y E G L D W L S R Q L V A A G
Rat Rattus norvegicus P84083 180 20511 S174 Y D G L D W L S H E L S K R _
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511094 180 20493 S174 Y E G L D W L S N E L S K R _
Chicken Gallus gallus P49702 180 20461 S174 Y D G L D W L S H E L S K R _
Frog Xenopus laevis P51644 180 20567 S174 Y E G L D W L S N E L S K R _
Zebra Danio Brachydanio rerio NP_956170 180 20354 S174 Y E G L D W L S N E L S K R _
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40945 180 20598 S174 Y E G L D W L S A E L A K K _
Honey Bee Apis mellifera XP_393787 180 20403 S174 Y E G L D W L S N E L A K K _
Nematode Worm Caenorhab. elegans Q10943 181 20503 S174 Y E G L D W L S N Q L K N R S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002302788 181 20661 S174 Y E G L D W L S N N I A N K A
Maize Zea mays P49076 181 20642 S174 Y E G L D W L S S N I A T K S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P36397 181 20590 S174 Y E G L D W L S N N I A S K A
Baker's Yeast Sacchar. cerevisiae P19146 181 20639 S174 Y E G L E W L S N N L K N Q S
Red Bread Mold Neurospora crassa Q7RVM2 185 20961 S177 F E G L D W L S T E L K K K S
Conservation
Percent
Protein Identity: 100 N.A. 88.8 89.4 N.A. 20.7 100 N.A. 91.6 97.7 91.6 93.8 N.A. 83.8 83.3 79.5 N.A.
Protein Similarity: 100 N.A. 96.1 90 N.A. 25.4 100 N.A. 98.3 98.8 98.3 97.7 N.A. 92.7 92.7 88.4 N.A.
P-Site Identity: 100 N.A. 85.7 100 N.A. 53.3 100 N.A. 85.7 100 85.7 85.7 N.A. 71.4 71.4 60 N.A.
P-Site Similarity: 100 N.A. 100 100 N.A. 73.3 100 N.A. 100 100 100 100 N.A. 92.8 100 80 N.A.
Percent
Protein Identity: 80.1 81.2 N.A. 81.2 68.5 77.8
Protein Similarity: 89.5 88.9 N.A. 88.9 86.1 88.1
P-Site Identity: 46.6 46.6 N.A. 46.6 46.6 60
P-Site Similarity: 80 73.3 N.A. 80 73.3 80
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 6 0 0 30 6 6 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 24 0 0 95 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 77 0 0 6 0 0 0 0 65 0 0 0 0 0 % E
% Phe: 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 100 0 0 0 0 0 0 0 0 0 0 0 6 % G
% His: 0 0 0 0 0 0 0 0 24 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 18 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 18 65 36 0 % K
% Leu: 0 0 0 100 0 0 100 0 0 0 83 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 53 24 0 0 18 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 12 0 0 0 6 0 % Q
% Arg: 0 0 0 0 0 0 0 0 6 0 0 0 0 53 0 % R
% Ser: 0 0 0 0 0 0 0 100 6 0 0 48 6 0 24 % S
% Thr: 0 0 0 0 0 0 0 0 6 0 0 0 6 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 6 0 0 0 % V
% Trp: 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 % W
% Tyr: 95 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 59 % _