Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARF5 All Species: 40
Human Site: T152 Identified Species: 55
UniProt: P84085 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P84085 NP_001653.1 180 20530 T152 L Q H L R S R T W Y V Q A T C
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001103974 180 20437 T152 L Q S L R N R T W Y V Q A T C
Dog Lupus familis XP_858890 164 18600 T136 L Q H L R S R T W Y V Q A T C
Cat Felis silvestris
Mouse Mus musculus Q8BGX0 574 63913 S540 H K L C C G R S W Y I Q G C D
Rat Rattus norvegicus P84083 180 20511 T152 L Q H L R S R T W Y V Q A T C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511094 180 20493 T152 L Q A L R N R T W Y V Q A T C
Chicken Gallus gallus P49702 180 20461 T152 L Q A L R S R T W Y V Q A T C
Frog Xenopus laevis P51644 180 20567 T152 L Q T L R N R T W Y V Q A T C
Zebra Danio Brachydanio rerio NP_956170 180 20354 T152 L Q S L R S R T W Y V Q A T C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40945 180 20598 H152 L N Q L R N R H W F I Q S T C
Honey Bee Apis mellifera XP_393787 180 20403 H152 L N S L R G R H W Y I Q S T C
Nematode Worm Caenorhab. elegans Q10943 181 20503 S152 L H S L R N R S W Y I Q A T C
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002302788 181 20661 H152 L H S L R Q R H W Y I Q S T C
Maize Zea mays P49076 181 20642 H152 L N S L R Q R H W Y I Q S T C
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P36397 181 20590 H152 L H S L R Q R H W Y I Q S T C
Baker's Yeast Sacchar. cerevisiae P19146 181 20639 P152 L H S I R N R P W F I Q S T C
Red Bread Mold Neurospora crassa Q7RVM2 185 20961 S155 L S S L R Q R S W Y I Q A T C
Conservation
Percent
Protein Identity: 100 N.A. 88.8 89.4 N.A. 20.7 100 N.A. 91.6 97.7 91.6 93.8 N.A. 83.8 83.3 79.5 N.A.
Protein Similarity: 100 N.A. 96.1 90 N.A. 25.4 100 N.A. 98.3 98.8 98.3 97.7 N.A. 92.7 92.7 88.4 N.A.
P-Site Identity: 100 N.A. 86.6 100 N.A. 26.6 100 N.A. 86.6 93.3 86.6 93.3 N.A. 53.3 60 66.6 N.A.
P-Site Similarity: 100 N.A. 93.3 100 N.A. 46.6 100 N.A. 93.3 93.3 93.3 93.3 N.A. 80 73.3 86.6 N.A.
Percent
Protein Identity: 80.1 81.2 N.A. 81.2 68.5 77.8
Protein Similarity: 89.5 88.9 N.A. 88.9 86.1 88.1
P-Site Identity: 60 60 N.A. 60 46.6 66.6
P-Site Similarity: 73.3 73.3 N.A. 73.3 80 80
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 12 0 0 0 0 0 0 0 0 0 59 0 0 % A
% Cys: 0 0 0 6 6 0 0 0 0 0 0 0 0 6 95 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 12 0 0 0 0 0 0 6 0 0 % G
% His: 6 24 18 0 0 0 0 30 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 6 0 0 0 0 0 0 53 0 0 0 0 % I
% Lys: 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 95 0 6 89 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 18 0 0 0 36 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 6 0 0 0 0 0 0 0 % P
% Gln: 0 48 6 0 0 24 0 0 0 0 0 100 0 0 0 % Q
% Arg: 0 0 0 0 95 0 100 0 0 0 0 0 0 0 0 % R
% Ser: 0 6 53 0 0 30 0 18 0 0 0 0 36 0 0 % S
% Thr: 0 0 6 0 0 0 0 48 0 0 0 0 0 95 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 48 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 89 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _