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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARHGAP8 All Species: 6.67
Human Site: S114 Identified Species: 13.33
UniProt: P85298 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P85298 NP_001017526.1 464 53484 S114 W P R L V S N S K L K R S S H
Chimpanzee Pan troglodytes XP_508398 562 63325 F112 R A R F L L R F C R A R L S G
Rhesus Macaque Macaca mulatta XP_001101907 504 57584 P128 T H L K W D D P Y Y D I A R H
Dog Lupus familis XP_851463 698 78707 S301 G R R V I T F S C C R M P P S
Cat Felis silvestris
Mouse Mus musculus Q9CXP4 425 48954 S80 V Y F H Y G L S S Q N K P S L
Rat Rattus norvegicus NP_001004242 425 48859 S80 V Y F H Y G L S S Q N K P S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416463 424 49139 Y79 C C R M P P S Y Q L N H T R L
Frog Xenopus laevis NP_001085153 420 48563 P75 F S C C R L P P C H E I D H V
Zebra Danio Brachydanio rerio NP_001017781 434 49569 N89 G R K V I V F N A C R M P P Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VTU3 476 54951 I113 T D K Q G R H I F G I Y A S R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_001022390 444 50636 Y99 G R P I V V V Y A Y R L P S S
Sea Urchin Strong. purpuratus XP_790928 337 38271
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 37.3 41.2 45.7 N.A. 74.5 74.7 N.A. N.A. 50.6 46.5 34.9 N.A. 29.8 N.A. 25.6 30.8
Protein Similarity: 100 51.2 54.5 53.8 N.A. 81.9 82.1 N.A. N.A. 64.4 61.2 52.5 N.A. 48.5 N.A. 44.6 43.9
P-Site Identity: 100 20 6.6 13.3 N.A. 13.3 13.3 N.A. N.A. 13.3 0 0 N.A. 6.6 N.A. 13.3 0
P-Site Similarity: 100 26.6 20 40 N.A. 20 20 N.A. N.A. 40 13.3 33.3 N.A. 26.6 N.A. 26.6 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 0 0 0 0 17 0 9 0 17 0 0 % A
% Cys: 9 9 9 9 0 0 0 0 25 17 0 0 0 0 0 % C
% Asp: 0 9 0 0 0 9 9 0 0 0 9 0 9 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % E
% Phe: 9 0 17 9 0 0 17 9 9 0 0 0 0 0 0 % F
% Gly: 25 0 0 0 9 17 0 0 0 9 0 0 0 0 9 % G
% His: 0 9 0 17 0 0 9 0 0 9 0 9 0 9 17 % H
% Ile: 0 0 0 9 17 0 0 9 0 0 9 17 0 0 0 % I
% Lys: 0 0 17 9 0 0 0 0 9 0 9 17 0 0 0 % K
% Leu: 0 0 9 9 9 17 17 0 0 17 0 9 9 0 25 % L
% Met: 0 0 0 9 0 0 0 0 0 0 0 17 0 0 0 % M
% Asn: 0 0 0 0 0 0 9 9 0 0 25 0 0 0 0 % N
% Pro: 0 9 9 0 9 9 9 17 0 0 0 0 42 17 0 % P
% Gln: 0 0 0 9 0 0 0 0 9 17 0 0 0 0 9 % Q
% Arg: 9 25 34 0 9 9 9 0 0 9 25 17 0 17 9 % R
% Ser: 0 9 0 0 0 9 9 34 17 0 0 0 9 50 17 % S
% Thr: 17 0 0 0 0 9 0 0 0 0 0 0 9 0 0 % T
% Val: 17 0 0 17 17 17 9 0 0 0 0 0 0 0 9 % V
% Trp: 9 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 17 0 0 17 0 0 17 9 17 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _