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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARHGAP8 All Species: 1.21
Human Site: S81 Identified Species: 2.42
UniProt: P85298 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P85298 NP_001017526.1 464 53484 S81 Y F H Y G L N S R N K P S L G
Chimpanzee Pan troglodytes XP_508398 562 63325 G79 W L G I E E S G R G R F P F H
Rhesus Macaque Macaca mulatta XP_001101907 504 57584 E95 L K L A S I D E K N W P S D E
Dog Lupus familis XP_851463 698 78707 P268 V P T A G Q D P A L S M D H P
Cat Felis silvestris
Mouse Mus musculus Q9CXP4 425 48954 H47 C C R L P P L H Q L N H Q R L
Rat Rattus norvegicus NP_001004242 425 48859 H47 C C R L P P L H Q L N H Q R L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416463 424 49139 Y46 E L D I N H P Y Y D V A R H G
Frog Xenopus laevis NP_001085153 420 48563 H42 T S D V C I G H P Y Y D I A R
Zebra Danio Brachydanio rerio NP_001017781 434 49569 S56 I K S L G D T S H L P W D D P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VTU3 476 54951 E80 E E D V N P L E D D F E D Q L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_001022390 444 50636 V66 F E T E L G G V E P F E D L F
Sea Urchin Strong. purpuratus XP_790928 337 38271
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 37.3 41.2 45.7 N.A. 74.5 74.7 N.A. N.A. 50.6 46.5 34.9 N.A. 29.8 N.A. 25.6 30.8
Protein Similarity: 100 51.2 54.5 53.8 N.A. 81.9 82.1 N.A. N.A. 64.4 61.2 52.5 N.A. 48.5 N.A. 44.6 43.9
P-Site Identity: 100 6.6 20 6.6 N.A. 0 0 N.A. N.A. 6.6 0 13.3 N.A. 0 N.A. 6.6 0
P-Site Similarity: 100 26.6 40 13.3 N.A. 6.6 6.6 N.A. N.A. 13.3 6.6 13.3 N.A. 6.6 N.A. 13.3 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 17 0 0 0 0 9 0 0 9 0 9 0 % A
% Cys: 17 17 0 0 9 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 25 0 0 9 17 0 9 17 0 9 34 17 0 % D
% Glu: 17 17 0 9 9 9 0 17 9 0 0 17 0 0 9 % E
% Phe: 9 9 0 0 0 0 0 0 0 0 17 9 0 9 9 % F
% Gly: 0 0 9 0 25 9 17 9 0 9 0 0 0 0 17 % G
% His: 0 0 9 0 0 9 0 25 9 0 0 17 0 17 9 % H
% Ile: 9 0 0 17 0 17 0 0 0 0 0 0 9 0 0 % I
% Lys: 0 17 0 0 0 0 0 0 9 0 9 0 0 0 0 % K
% Leu: 9 17 9 25 9 9 25 0 0 34 0 0 0 17 25 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % M
% Asn: 0 0 0 0 17 0 9 0 0 17 17 0 0 0 0 % N
% Pro: 0 9 0 0 17 25 9 9 9 9 9 17 9 0 17 % P
% Gln: 0 0 0 0 0 9 0 0 17 0 0 0 17 9 0 % Q
% Arg: 0 0 17 0 0 0 0 0 17 0 9 0 9 17 9 % R
% Ser: 0 9 9 0 9 0 9 17 0 0 9 0 17 0 0 % S
% Thr: 9 0 17 0 0 0 9 0 0 0 0 0 0 0 0 % T
% Val: 9 0 0 17 0 0 0 9 0 0 9 0 0 0 0 % V
% Trp: 9 0 0 0 0 0 0 0 0 0 9 9 0 0 0 % W
% Tyr: 9 0 0 9 0 0 0 9 9 9 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _