KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARHGAP8
All Species:
6.06
Human Site:
T206
Identified Species:
12.12
UniProt:
P85298
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P85298
NP_001017526.1
464
53484
T206
Q
S
L
H
E
G
R
T
P
P
P
T
K
T
P
Chimpanzee
Pan troglodytes
XP_508398
562
63325
Y204
E
V
A
G
D
D
K
Y
G
R
K
I
I
V
F
Rhesus Macaque
Macaca mulatta
XP_001101907
504
57584
I220
D
R
K
Y
K
K
N
I
K
A
L
Y
I
V
H
Dog
Lupus familis
XP_851463
698
78707
S393
R
S
L
H
K
G
R
S
S
P
P
A
K
T
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXP4
425
48954
K172
E
K
L
Q
N
L
H
K
G
Q
P
P
P
P
T
Rat
Rattus norvegicus
NP_001004242
425
48859
K172
E
K
L
R
N
L
H
K
G
Q
T
A
P
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416463
424
49139
L171
F
G
K
K
V
T
Y
L
N
Y
L
S
D
L
R
Frog
Xenopus laevis
NP_001085153
420
48563
L167
H
K
F
G
K
K
V
L
Y
M
K
D
L
N
D
Zebra Danio
Brachydanio rerio
NP_001017781
434
49569
K181
F
K
P
I
I
S
F
K
F
G
R
K
I
N
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VTU3
476
54951
S205
N
F
F
S
P
F
I
S
D
K
F
R
K
K
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001022390
444
50636
K191
F
K
G
F
I
S
S
K
F
E
N
K
F
H
Y
Sea Urchin
Strong. purpuratus
XP_790928
337
38271
Y84
H
D
D
Q
L
V
A
Y
Y
K
A
K
Q
T
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
37.3
41.2
45.7
N.A.
74.5
74.7
N.A.
N.A.
50.6
46.5
34.9
N.A.
29.8
N.A.
25.6
30.8
Protein Similarity:
100
51.2
54.5
53.8
N.A.
81.9
82.1
N.A.
N.A.
64.4
61.2
52.5
N.A.
48.5
N.A.
44.6
43.9
P-Site Identity:
100
0
0
66.6
N.A.
13.3
6.6
N.A.
N.A.
0
0
0
N.A.
6.6
N.A.
0
6.6
P-Site Similarity:
100
20
13.3
86.6
N.A.
20
13.3
N.A.
N.A.
6.6
6.6
0
N.A.
13.3
N.A.
0
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
9
0
0
9
9
17
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
9
9
0
9
9
0
0
9
0
0
9
9
0
9
% D
% Glu:
25
0
0
0
9
0
0
0
0
9
0
0
0
0
0
% E
% Phe:
25
9
17
9
0
9
9
0
17
0
9
0
9
0
9
% F
% Gly:
0
9
9
17
0
17
0
0
25
9
0
0
0
0
0
% G
% His:
17
0
0
17
0
0
17
0
0
0
0
0
0
9
9
% H
% Ile:
0
0
0
9
17
0
9
9
0
0
0
9
25
0
0
% I
% Lys:
0
42
17
9
25
17
9
34
9
17
17
25
25
9
0
% K
% Leu:
0
0
34
0
9
17
0
17
0
0
17
0
9
9
9
% L
% Met:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
9
0
0
0
17
0
9
0
9
0
9
0
0
17
0
% N
% Pro:
0
0
9
0
9
0
0
0
9
17
25
9
17
17
17
% P
% Gln:
9
0
0
17
0
0
0
0
0
17
0
0
9
0
0
% Q
% Arg:
9
9
0
9
0
0
17
0
0
9
9
9
0
0
9
% R
% Ser:
0
17
0
9
0
17
9
17
9
0
0
9
0
0
0
% S
% Thr:
0
0
0
0
0
9
0
9
0
0
9
9
0
25
17
% T
% Val:
0
9
0
0
9
9
9
0
0
0
0
0
0
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
9
17
17
9
0
9
0
0
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _