KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARHGAP8
All Species:
4.85
Human Site:
T312
Identified Species:
9.7
UniProt:
P85298
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P85298
NP_001017526.1
464
53484
T312
E
L
P
Q
P
L
L
T
F
Q
A
Y
E
Q
I
Chimpanzee
Pan troglodytes
XP_508398
562
63325
K308
I
S
F
K
F
G
Q
K
I
F
Y
V
N
Y
L
Rhesus Macaque
Macaca mulatta
XP_001101907
504
57584
I326
P
E
Q
E
P
I
P
I
V
L
R
E
T
V
A
Dog
Lupus familis
XP_851463
698
78707
T499
E
L
P
Q
P
L
L
T
F
K
A
Y
E
Q
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXP4
425
48954
P276
K
T
F
L
R
E
L
P
Q
P
L
L
T
F
Q
Rat
Rattus norvegicus
NP_001004242
425
48859
P276
K
T
F
L
R
E
L
P
Q
P
L
L
T
F
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416463
424
49139
V275
S
I
Q
T
I
K
D
V
Q
K
L
Y
N
Q
G
Frog
Xenopus laevis
NP_001085153
420
48563
V271
S
I
H
I
I
K
D
V
Q
K
L
Y
N
V
G
Zebra Danio
Brachydanio rerio
NP_001017781
434
49569
S285
T
E
G
I
F
R
R
S
A
N
V
S
L
V
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VTU3
476
54951
D309
L
S
I
T
G
V
I
D
T
E
G
I
F
R
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001022390
444
50636
R295
A
N
I
G
S
I
K
R
L
Q
D
R
I
N
K
Sea Urchin
Strong. purpuratus
XP_790928
337
38271
L188
D
V
H
V
P
A
L
L
L
K
A
F
F
R
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
37.3
41.2
45.7
N.A.
74.5
74.7
N.A.
N.A.
50.6
46.5
34.9
N.A.
29.8
N.A.
25.6
30.8
Protein Similarity:
100
51.2
54.5
53.8
N.A.
81.9
82.1
N.A.
N.A.
64.4
61.2
52.5
N.A.
48.5
N.A.
44.6
43.9
P-Site Identity:
100
0
6.6
93.3
N.A.
6.6
6.6
N.A.
N.A.
13.3
6.6
0
N.A.
0
N.A.
6.6
20
P-Site Similarity:
100
13.3
20
100
N.A.
13.3
13.3
N.A.
N.A.
26.6
20
6.6
N.A.
26.6
N.A.
13.3
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
9
0
0
9
0
25
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
0
17
9
0
0
9
0
0
0
0
% D
% Glu:
17
17
0
9
0
17
0
0
0
9
0
9
17
0
9
% E
% Phe:
0
0
25
0
17
0
0
0
17
9
0
9
17
17
0
% F
% Gly:
0
0
9
9
9
9
0
0
0
0
9
0
0
0
17
% G
% His:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
17
17
17
17
17
9
9
9
0
0
9
9
0
17
% I
% Lys:
17
0
0
9
0
17
9
9
0
34
0
0
0
0
17
% K
% Leu:
9
17
0
17
0
17
42
9
17
9
34
17
9
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
0
0
0
9
0
0
25
9
0
% N
% Pro:
9
0
17
0
34
0
9
17
0
17
0
0
0
0
0
% P
% Gln:
0
0
17
17
0
0
9
0
34
17
0
0
0
25
17
% Q
% Arg:
0
0
0
0
17
9
9
9
0
0
9
9
0
17
9
% R
% Ser:
17
17
0
0
9
0
0
9
0
0
0
9
0
0
0
% S
% Thr:
9
17
0
17
0
0
0
17
9
0
0
0
25
0
0
% T
% Val:
0
9
0
9
0
9
0
17
9
0
9
9
0
25
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
9
34
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _