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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARHGAP8
All Species:
1.21
Human Site:
T414
Identified Species:
2.42
UniProt:
P85298
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P85298
NP_001017526.1
464
53484
T414
Y
Y
E
K
I
F
S
T
P
E
A
P
G
E
H
Chimpanzee
Pan troglodytes
XP_508398
562
63325
T410
I
F
R
R
S
A
N
T
Q
V
V
R
E
V
Q
Rhesus Macaque
Macaca mulatta
XP_001101907
504
57584
E428
V
L
Q
T
L
P
E
E
N
Y
Q
V
L
R
F
Dog
Lupus familis
XP_851463
698
78707
A601
Y
Y
G
K
V
F
S
A
P
E
A
R
G
E
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXP4
425
48954
D378
E
L
L
I
E
Y
Y
D
K
V
F
S
C
Q
E
Rat
Rattus norvegicus
NP_001004242
425
48859
D378
E
L
L
I
E
Y
Y
D
K
V
F
S
A
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416463
424
49139
V377
T
A
S
S
L
A
C
V
F
G
L
N
L
I
W
Frog
Xenopus laevis
NP_001085153
420
48563
I373
T
S
S
N
L
G
C
I
F
G
L
N
L
I
W
Zebra Danio
Brachydanio rerio
NP_001017781
434
49569
K387
S
A
E
S
E
I
N
K
M
T
N
A
N
L
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VTU3
476
54951
V411
I
V
E
F
L
V
R
V
M
D
C
E
D
L
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001022390
444
50636
L397
A
E
N
S
K
V
N
L
M
T
A
N
N
L
S
Sea Urchin
Strong. purpuratus
XP_790928
337
38271
N290
L
S
A
M
A
Q
I
N
S
F
I
A
T
I
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
37.3
41.2
45.7
N.A.
74.5
74.7
N.A.
N.A.
50.6
46.5
34.9
N.A.
29.8
N.A.
25.6
30.8
Protein Similarity:
100
51.2
54.5
53.8
N.A.
81.9
82.1
N.A.
N.A.
64.4
61.2
52.5
N.A.
48.5
N.A.
44.6
43.9
P-Site Identity:
100
6.6
0
66.6
N.A.
0
0
N.A.
N.A.
0
0
6.6
N.A.
6.6
N.A.
6.6
0
P-Site Similarity:
100
26.6
13.3
73.3
N.A.
13.3
13.3
N.A.
N.A.
6.6
6.6
13.3
N.A.
26.6
N.A.
13.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
17
9
0
9
17
0
9
0
0
25
17
9
0
9
% A
% Cys:
0
0
0
0
0
0
17
0
0
0
9
0
9
0
0
% C
% Asp:
0
0
0
0
0
0
0
17
0
9
0
0
9
0
0
% D
% Glu:
17
9
25
0
25
0
9
9
0
17
0
9
9
17
17
% E
% Phe:
0
9
0
9
0
17
0
0
17
9
17
0
0
0
9
% F
% Gly:
0
0
9
0
0
9
0
0
0
17
0
0
17
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% H
% Ile:
17
0
0
17
9
9
9
9
0
0
9
0
0
25
0
% I
% Lys:
0
0
0
17
9
0
0
9
17
0
0
0
0
0
0
% K
% Leu:
9
25
17
0
34
0
0
9
0
0
17
0
25
25
9
% L
% Met:
0
0
0
9
0
0
0
0
25
0
0
0
0
0
0
% M
% Asn:
0
0
9
9
0
0
25
9
9
0
9
25
17
0
9
% N
% Pro:
0
0
0
0
0
9
0
0
17
0
0
9
0
0
9
% P
% Gln:
0
0
9
0
0
9
0
0
9
0
9
0
0
17
9
% Q
% Arg:
0
0
9
9
0
0
9
0
0
0
0
17
0
9
0
% R
% Ser:
9
17
17
25
9
0
17
0
9
0
0
17
0
0
9
% S
% Thr:
17
0
0
9
0
0
0
17
0
17
0
0
9
0
0
% T
% Val:
9
9
0
0
9
17
0
17
0
25
9
9
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% W
% Tyr:
17
17
0
0
0
17
17
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _