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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARHGAP8
All Species:
7.88
Human Site:
Y169
Identified Species:
15.76
UniProt:
P85298
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P85298
NP_001017526.1
464
53484
Y169
K
F
G
K
K
V
I
Y
F
N
Y
L
S
E
L
Chimpanzee
Pan troglodytes
XP_508398
562
63325
S167
E
M
P
D
F
P
K
S
D
D
S
K
S
S
S
Rhesus Macaque
Macaca mulatta
XP_001101907
504
57584
S183
T
L
D
Q
Y
V
E
S
D
Y
T
L
L
Y
L
Dog
Lupus familis
XP_851463
698
78707
Y356
K
F
G
K
K
V
I
Y
F
N
S
L
S
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXP4
425
48954
K135
I
S
H
K
F
G
K
K
V
T
Y
C
S
N
L
Rat
Rattus norvegicus
NP_001004242
425
48859
K135
I
S
H
K
F
G
K
K
V
T
Y
C
S
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416463
424
49139
K134
K
E
F
D
R
K
Y
K
K
N
L
K
A
L
Y
Frog
Xenopus laevis
NP_001085153
420
48563
K130
A
Y
K
E
F
D
R
K
Y
K
K
N
L
K
A
Zebra Danio
Brachydanio rerio
NP_001017781
434
49569
Y144
L
S
W
L
R
D
A
Y
R
E
F
D
R
K
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VTU3
476
54951
N168
P
S
A
Q
F
L
W
N
S
Y
K
E
L
D
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001022390
444
50636
Y154
V
R
W
L
F
Q
A
Y
K
Q
L
D
R
R
F
Sea Urchin
Strong. purpuratus
XP_790928
337
38271
S47
H
I
V
S
V
K
F
S
R
K
V
T
Y
I
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
37.3
41.2
45.7
N.A.
74.5
74.7
N.A.
N.A.
50.6
46.5
34.9
N.A.
29.8
N.A.
25.6
30.8
Protein Similarity:
100
51.2
54.5
53.8
N.A.
81.9
82.1
N.A.
N.A.
64.4
61.2
52.5
N.A.
48.5
N.A.
44.6
43.9
P-Site Identity:
100
6.6
20
93.3
N.A.
26.6
26.6
N.A.
N.A.
13.3
0
6.6
N.A.
0
N.A.
6.6
0
P-Site Similarity:
100
20
26.6
93.3
N.A.
26.6
26.6
N.A.
N.A.
26.6
26.6
26.6
N.A.
20
N.A.
6.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
0
0
0
17
0
0
0
0
0
9
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% C
% Asp:
0
0
9
17
0
17
0
0
17
9
0
17
0
9
0
% D
% Glu:
9
9
0
9
0
0
9
0
0
9
0
9
0
17
0
% E
% Phe:
0
17
9
0
50
0
9
0
17
0
9
0
0
0
9
% F
% Gly:
0
0
17
0
0
17
0
0
0
0
0
0
0
0
0
% G
% His:
9
0
17
0
0
0
0
0
0
0
0
0
0
0
9
% H
% Ile:
17
9
0
0
0
0
17
0
0
0
0
0
0
9
0
% I
% Lys:
25
0
9
34
17
17
25
34
17
17
17
17
0
17
0
% K
% Leu:
9
9
0
17
0
9
0
0
0
0
17
25
25
9
42
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
0
25
0
9
0
17
0
% N
% Pro:
9
0
9
0
0
9
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
17
0
9
0
0
0
9
0
0
0
0
0
% Q
% Arg:
0
9
0
0
17
0
9
0
17
0
0
0
17
9
9
% R
% Ser:
0
34
0
9
0
0
0
25
9
0
17
0
42
9
9
% S
% Thr:
9
0
0
0
0
0
0
0
0
17
9
9
0
0
0
% T
% Val:
9
0
9
0
9
25
0
0
17
0
9
0
0
0
0
% V
% Trp:
0
0
17
0
0
0
9
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
9
0
9
34
9
17
25
0
9
9
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _