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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARHGAP8
All Species:
5.76
Human Site:
Y194
Identified Species:
11.52
UniProt:
P85298
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P85298
NP_001017526.1
464
53484
Y194
I
P
P
E
V
L
R
Y
D
E
K
L
Q
S
L
Chimpanzee
Pan troglodytes
XP_508398
562
63325
R192
D
P
Y
Y
D
I
A
R
H
Q
I
V
E
V
A
Rhesus Macaque
Macaca mulatta
XP_001101907
504
57584
A208
S
L
S
W
L
R
D
A
Y
R
E
F
D
R
K
Dog
Lupus familis
XP_851463
698
78707
Y381
V
P
P
E
V
L
R
Y
D
E
K
L
R
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXP4
425
48954
V160
Q
L
L
I
P
P
E
V
V
R
Y
D
E
K
L
Rat
Rattus norvegicus
NP_001004242
425
48859
V160
Q
L
L
I
P
P
E
V
V
R
Y
D
E
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416463
424
49139
L159
L
W
N
I
F
K
P
L
I
S
H
K
F
G
K
Frog
Xenopus laevis
NP_001085153
420
48563
K155
K
V
L
W
N
I
F
K
P
V
I
S
H
K
F
Zebra Danio
Brachydanio rerio
NP_001017781
434
49569
T169
H
P
T
M
F
I
R
T
I
L
I
L
F
K
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VTU3
476
54951
I193
V
V
H
P
T
W
F
I
R
V
I
W
N
F
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001022390
444
50636
I179
H
P
T
R
F
I
R
I
I
F
S
L
F
K
G
Sea Urchin
Strong. purpuratus
XP_790928
337
38271
A72
M
K
K
V
E
I
P
A
V
I
Q
S
H
D
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
37.3
41.2
45.7
N.A.
74.5
74.7
N.A.
N.A.
50.6
46.5
34.9
N.A.
29.8
N.A.
25.6
30.8
Protein Similarity:
100
51.2
54.5
53.8
N.A.
81.9
82.1
N.A.
N.A.
64.4
61.2
52.5
N.A.
48.5
N.A.
44.6
43.9
P-Site Identity:
100
6.6
0
86.6
N.A.
6.6
6.6
N.A.
N.A.
0
0
20
N.A.
0
N.A.
20
0
P-Site Similarity:
100
33.3
13.3
100
N.A.
13.3
13.3
N.A.
N.A.
6.6
6.6
26.6
N.A.
6.6
N.A.
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
17
0
0
0
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
9
0
9
0
17
0
0
17
9
9
9
% D
% Glu:
0
0
0
17
9
0
17
0
0
17
9
0
25
0
0
% E
% Phe:
0
0
0
0
25
0
17
0
0
9
0
9
25
9
17
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
9
% G
% His:
17
0
9
0
0
0
0
0
9
0
9
0
17
0
0
% H
% Ile:
9
0
0
25
0
42
0
17
25
9
34
0
0
0
0
% I
% Lys:
9
9
9
0
0
9
0
9
0
0
17
9
0
42
17
% K
% Leu:
9
25
25
0
9
17
0
9
0
9
0
34
0
0
34
% L
% Met:
9
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
9
0
0
0
0
0
0
0
9
0
0
% N
% Pro:
0
42
17
9
17
17
17
0
9
0
0
0
0
0
9
% P
% Gln:
17
0
0
0
0
0
0
0
0
9
9
0
9
0
0
% Q
% Arg:
0
0
0
9
0
9
34
9
9
25
0
0
9
9
0
% R
% Ser:
9
0
9
0
0
0
0
0
0
9
9
17
0
17
0
% S
% Thr:
0
0
17
0
9
0
0
9
0
0
0
0
0
0
0
% T
% Val:
17
17
0
9
17
0
0
17
25
17
0
9
0
9
0
% V
% Trp:
0
9
0
17
0
9
0
0
0
0
0
9
0
0
0
% W
% Tyr:
0
0
9
9
0
0
0
17
9
0
17
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _