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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARHGAP8 All Species: 4.55
Human Site: Y408 Identified Species: 9.09
UniProt: P85298 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P85298 NP_001017526.1 464 53484 Y408 T E L L I E Y Y E K I F S T P
Chimpanzee Pan troglodytes XP_508398 562 63325 F404 A L T T E G I F R R S A N T Q
Rhesus Macaque Macaca mulatta XP_001101907 504 57584 L422 V A E T L Q V L Q T L P E E N
Dog Lupus familis XP_851463 698 78707 Y595 T E L L I E Y Y G K V F S A P
Cat Felis silvestris
Mouse Mus musculus Q9CXP4 425 48954 L372 P L N L F T E L L I E Y Y D K
Rat Rattus norvegicus NP_001004242 425 48859 L372 P L N L F T E L L I E Y Y D K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416463 424 49139 A371 S I Y N R M T A S S L A C V F
Frog Xenopus laevis NP_001085153 420 48563 S367 H I Q N K M T S S N L G C I F
Zebra Danio Brachydanio rerio NP_001017781 434 49569 A381 Q F L A Q V S A E S E I N K M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VTU3 476 54951 V405 Y E L F K Y I V E F L V R V M
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_001022390 444 50636 E391 K F L T R V A E N S K V N L M
Sea Urchin Strong. purpuratus XP_790928 337 38271 S284 R D A S A S L S A M A Q I N S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 37.3 41.2 45.7 N.A. 74.5 74.7 N.A. N.A. 50.6 46.5 34.9 N.A. 29.8 N.A. 25.6 30.8
Protein Similarity: 100 51.2 54.5 53.8 N.A. 81.9 82.1 N.A. N.A. 64.4 61.2 52.5 N.A. 48.5 N.A. 44.6 43.9
P-Site Identity: 100 6.6 0 80 N.A. 6.6 6.6 N.A. N.A. 0 0 13.3 N.A. 20 N.A. 6.6 0
P-Site Similarity: 100 26.6 26.6 86.6 N.A. 13.3 13.3 N.A. N.A. 13.3 6.6 20 N.A. 26.6 N.A. 13.3 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 9 9 9 0 9 17 9 0 9 17 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 17 0 0 % C
% Asp: 0 9 0 0 0 0 0 0 0 0 0 0 0 17 0 % D
% Glu: 0 25 9 0 9 17 17 9 25 0 25 0 9 9 0 % E
% Phe: 0 17 0 9 17 0 0 9 0 9 0 17 0 0 17 % F
% Gly: 0 0 0 0 0 9 0 0 9 0 0 9 0 0 0 % G
% His: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 17 0 0 17 0 17 0 0 17 9 9 9 9 0 % I
% Lys: 9 0 0 0 17 0 0 0 0 17 9 0 0 9 17 % K
% Leu: 0 25 42 34 9 0 9 25 17 0 34 0 0 9 0 % L
% Met: 0 0 0 0 0 17 0 0 0 9 0 0 0 0 25 % M
% Asn: 0 0 17 17 0 0 0 0 9 9 0 0 25 9 9 % N
% Pro: 17 0 0 0 0 0 0 0 0 0 0 9 0 0 17 % P
% Gln: 9 0 9 0 9 9 0 0 9 0 0 9 0 0 9 % Q
% Arg: 9 0 0 0 17 0 0 0 9 9 0 0 9 0 0 % R
% Ser: 9 0 0 9 0 9 9 17 17 25 9 0 17 0 9 % S
% Thr: 17 0 9 25 0 17 17 0 0 9 0 0 0 17 0 % T
% Val: 9 0 0 0 0 17 9 9 0 0 9 17 0 17 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 9 0 0 9 17 17 0 0 0 17 17 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _