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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNFAIP6
All Species:
20
Human Site:
S254
Identified Species:
48.89
UniProt:
P98066
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P98066
NP_009046.2
277
31203
S254
M
D
P
V
S
K
S
S
Q
G
K
N
T
S
T
Chimpanzee
Pan troglodytes
XP_516218
277
31199
S254
M
D
P
V
S
K
S
S
Q
G
K
N
T
S
T
Rhesus Macaque
Macaca mulatta
XP_001083111
277
31039
S254
V
D
P
V
S
K
S
S
Q
G
K
N
T
S
T
Dog
Lupus familis
XP_533354
344
38609
S321
V
D
P
L
S
K
S
S
Q
G
K
N
T
S
T
Cat
Felis silvestris
Mouse
Mus musculus
O08859
275
30906
S253
T
V
D
P
A
S
K
S
S
Q
A
K
N
T
S
Rat
Rattus norvegicus
NP_445834
275
30988
S253
T
V
D
P
A
P
K
S
N
Q
G
K
N
T
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507251
277
31151
S254
V
D
P
V
S
K
P
S
D
G
K
N
S
S
T
Chicken
Gallus gallus
NP_001032926
275
30733
A253
T
I
D
V
P
S
K
A
G
D
G
K
N
T
T
Frog
Xenopus laevis
NP_001088914
266
30680
K243
I
G
G
G
F
Q
I
K
Y
T
A
V
D
S
E
Zebra Danio
Brachydanio rerio
NP_001035333
271
30510
G248
S
D
S
S
V
T
A
G
G
F
K
L
Q
Y
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97.1
74.1
N.A.
90.2
89.1
N.A.
87
79.7
68.9
67.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
98.5
79
N.A.
95.3
94.9
N.A.
94.5
90.2
81.5
81.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
86.6
N.A.
6.6
13.3
N.A.
73.3
13.3
6.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
26.6
26.6
N.A.
86.6
26.6
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
20
0
10
10
0
0
20
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
60
30
0
0
0
0
0
10
10
0
0
10
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% E
% Phe:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
10
10
10
0
0
0
10
20
50
20
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
10
0
0
0
0
10
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
50
30
10
0
0
60
30
0
0
0
% K
% Leu:
0
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% L
% Met:
20
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
0
50
30
0
0
% N
% Pro:
0
0
50
20
10
10
10
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
10
0
0
40
20
0
0
10
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
0
10
10
50
20
40
70
10
0
0
0
10
60
10
% S
% Thr:
30
0
0
0
0
10
0
0
0
10
0
0
40
30
70
% T
% Val:
30
20
0
50
10
0
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _