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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHC2
All Species:
8.48
Human Site:
Y414
Identified Species:
20.74
UniProt:
P98077
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P98077
NP_036567.2
582
61916
Y414
P
D
H
E
E
H
L
Y
V
N
T
Q
G
L
D
Chimpanzee
Pan troglodytes
XP_513843
473
51606
K325
V
N
V
Q
N
L
D
K
A
R
Q
A
V
G
G
Rhesus Macaque
Macaca mulatta
XP_001112447
583
62797
D424
P
G
R
E
L
F
D
D
P
S
Y
V
N
V
Q
Dog
Lupus familis
XP_854707
427
46569
F279
D
S
P
K
K
D
L
F
D
M
R
P
F
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMC3
573
61753
Y395
H
D
Y
E
E
H
L
Y
V
N
T
Q
G
L
D
Rat
Rattus norvegicus
O70142
573
61752
Y395
H
D
Y
E
E
H
L
Y
V
N
T
Q
G
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512200
548
59956
N380
Y
E
E
H
M
Y
V
N
T
Q
S
W
E
V
E
Chicken
Gallus gallus
XP_001233682
444
48762
K296
A
P
E
E
S
P
K
K
D
L
F
D
M
R
P
Frog
Xenopus laevis
Q8AY68
465
51711
D317
N
R
P
D
L
F
D
D
P
S
Y
V
N
V
Q
Zebra Danio
Brachydanio rerio
NP_001038438
501
56025
V347
L
D
N
L
E
A
S
V
V
G
R
R
P
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43.8
44.9
65.1
N.A.
85.4
86.2
N.A.
68.7
54.1
44.3
55.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
57.2
57.9
69
N.A.
89.8
90.7
N.A.
76.1
62
56.5
65.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
13.3
13.3
N.A.
86.6
86.6
N.A.
0
6.6
0
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
26.6
33.3
N.A.
93.3
93.3
N.A.
40
6.6
20
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
10
0
0
10
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
40
0
10
0
10
30
20
20
0
0
10
0
0
40
% D
% Glu:
0
10
20
50
40
0
0
0
0
0
0
0
10
20
10
% E
% Phe:
0
0
0
0
0
20
0
10
0
0
10
0
10
0
0
% F
% Gly:
0
10
0
0
0
0
0
0
0
10
0
0
30
10
10
% G
% His:
20
0
10
10
0
30
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
10
0
10
20
0
0
0
0
0
0
0
% K
% Leu:
10
0
0
10
20
10
40
0
0
10
0
0
0
30
0
% L
% Met:
0
0
0
0
10
0
0
0
0
10
0
0
10
0
0
% M
% Asn:
10
10
10
0
10
0
0
10
0
30
0
0
20
0
0
% N
% Pro:
20
10
20
0
0
10
0
0
20
0
0
10
10
0
10
% P
% Gln:
0
0
0
10
0
0
0
0
0
10
10
30
0
0
20
% Q
% Arg:
0
10
10
0
0
0
0
0
0
10
20
10
0
10
0
% R
% Ser:
0
10
0
0
10
0
10
0
0
20
10
0
0
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
10
0
30
0
0
0
0
% T
% Val:
10
0
10
0
0
0
10
10
40
0
0
20
10
30
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
10
0
20
0
0
10
0
30
0
0
20
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _