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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPG2
All Species:
5.76
Human Site:
S2251
Identified Species:
12.67
UniProt:
P98160
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P98160
NP_005520.4
4391
468798
S2251
I
P
P
V
R
I
E
S
S
S
S
T
V
A
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001099299
4392
468662
S2252
D
P
P
V
R
I
E
S
S
S
S
T
V
A
E
Dog
Lupus familis
XP_535371
2720
290354
P690
M
P
A
Q
P
G
M
P
P
L
S
S
T
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q05793
3707
398275
E1677
P
L
T
K
E
S
L
E
V
Q
I
H
P
S
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518520
1150
124768
Chicken
Gallus gallus
NP_001001876
4071
432826
P2041
S
I
E
V
V
V
V
P
G
A
A
P
P
V
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001120939
3407
371297
F1377
G
A
R
E
S
Q
D
F
E
I
V
F
R
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001027037
4179
461773
G2103
P
L
I
T
D
E
S
G
A
V
Q
D
T
E
N
Honey Bee
Apis mellifera
XP_393220
3382
373579
T1352
I
Q
P
D
I
P
L
T
Y
S
V
P
F
R
E
Nematode Worm
Caenorhab. elegans
Q06561
3375
369033
N1345
C
W
V
P
G
N
S
N
V
Q
L
R
W
S
R
Sea Urchin
Strong. purpuratus
XP_001186142
2326
251883
G295
C
D
C
K
D
N
V
G
G
D
S
C
N
F
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.8
51.7
N.A.
72.7
N.A.
N.A.
20.8
58.1
N.A.
45.2
N.A.
22.1
25.7
24.2
24.2
Protein Similarity:
100
N.A.
98.6
54.6
N.A.
77.8
N.A.
N.A.
23.2
69.8
N.A.
57.4
N.A.
35.9
39.4
37.9
34.7
P-Site Identity:
100
N.A.
93.3
13.3
N.A.
0
N.A.
N.A.
0
6.6
N.A.
6.6
N.A.
0
26.6
0
6.6
P-Site Similarity:
100
N.A.
93.3
26.6
N.A.
6.6
N.A.
N.A.
0
26.6
N.A.
13.3
N.A.
6.6
33.3
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
0
0
0
0
10
10
10
0
0
19
0
% A
% Cys:
19
0
10
0
0
0
0
0
0
0
0
10
0
0
10
% C
% Asp:
10
10
0
10
19
0
10
0
0
10
0
10
0
0
0
% D
% Glu:
0
0
10
10
10
10
19
10
10
0
0
0
0
19
37
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
10
10
10
0
% F
% Gly:
10
0
0
0
10
10
0
19
19
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
19
10
10
0
10
19
0
0
0
10
10
0
0
0
0
% I
% Lys:
0
0
0
19
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
19
0
0
0
0
19
0
0
10
10
0
0
0
10
% L
% Met:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
19
0
10
0
0
0
0
10
0
10
% N
% Pro:
19
28
28
10
10
10
0
19
10
0
0
19
19
0
0
% P
% Gln:
0
10
0
10
0
10
0
0
0
19
10
0
0
10
0
% Q
% Arg:
0
0
10
0
19
0
0
0
0
0
0
10
10
10
28
% R
% Ser:
10
0
0
0
10
10
19
19
19
28
37
10
0
19
0
% S
% Thr:
0
0
10
10
0
0
0
10
0
0
0
19
19
0
0
% T
% Val:
0
0
10
28
10
10
19
0
19
10
19
0
19
10
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _