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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HSPG2 All Species: 6.06
Human Site: S2302 Identified Species: 13.33
UniProt: P98160 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P98160 NP_005520.4 4391 468798 S2302 R L Y I F Q A S P A D A G Q Y
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001099299 4392 468662 S2303 R L Y I F Q A S P A D A G Q Y
Dog Lupus familis XP_535371 2720 290354 R741 D S Y G G F L R Y K V R Y E L
Cat Felis silvestris
Mouse Mus musculus Q05793 3707 398275 S1728 A Q Q R H Q G S E L H F P S V
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518520 1150 124768
Chicken Gallus gallus NP_001001876 4071 432826 S2092 L P A G H Q V S G S R L R V P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001120939 3407 371297 H1428 S S S I S G V H M D V A V P E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001027037 4179 461773 L2154 G G R L S Y S L I V E S Y G N
Honey Bee Apis mellifera XP_393220 3382 373579 I1403 E W M T A T Y I S D I S L D T
Nematode Worm Caenorhab. elegans Q06561 3375 369033 Q1396 P S D N T P L Q S E P V Q L N
Sea Urchin Strong. purpuratus XP_001186142 2326 251883 P346 L R V T L Q S P S D P R D V A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 97.8 51.7 N.A. 72.7 N.A. N.A. 20.8 58.1 N.A. 45.2 N.A. 22.1 25.7 24.2 24.2
Protein Similarity: 100 N.A. 98.6 54.6 N.A. 77.8 N.A. N.A. 23.2 69.8 N.A. 57.4 N.A. 35.9 39.4 37.9 34.7
P-Site Identity: 100 N.A. 100 6.6 N.A. 13.3 N.A. N.A. 0 13.3 N.A. 13.3 N.A. 0 0 0 6.6
P-Site Similarity: 100 N.A. 100 13.3 N.A. 13.3 N.A. N.A. 0 20 N.A. 13.3 N.A. 26.6 6.6 0 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 10 0 10 0 19 0 0 19 0 28 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 10 0 0 0 0 0 0 28 19 0 10 10 0 % D
% Glu: 10 0 0 0 0 0 0 0 10 10 10 0 0 10 10 % E
% Phe: 0 0 0 0 19 10 0 0 0 0 0 10 0 0 0 % F
% Gly: 10 10 0 19 10 10 10 0 10 0 0 0 19 10 0 % G
% His: 0 0 0 0 19 0 0 10 0 0 10 0 0 0 0 % H
% Ile: 0 0 0 28 0 0 0 10 10 0 10 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % K
% Leu: 19 19 0 10 10 0 19 10 0 10 0 10 10 10 10 % L
% Met: 0 0 10 0 0 0 0 0 10 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 19 % N
% Pro: 10 10 0 0 0 10 0 10 19 0 19 0 10 10 10 % P
% Gln: 0 10 10 0 0 46 0 10 0 0 0 0 10 19 0 % Q
% Arg: 19 10 10 10 0 0 0 10 0 0 10 19 10 0 0 % R
% Ser: 10 28 10 0 19 0 19 37 28 10 0 19 0 10 0 % S
% Thr: 0 0 0 19 10 10 0 0 0 0 0 0 0 0 10 % T
% Val: 0 0 10 0 0 0 19 0 0 10 19 10 10 19 10 % V
% Trp: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 28 0 0 10 10 0 10 0 0 0 19 0 19 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _