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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPG2
All Species:
6.67
Human Site:
S2576
Identified Species:
14.67
UniProt:
P98160
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P98160
NP_005520.4
4391
468798
S2576
K
R
G
G
S
L
P
S
R
H
Q
I
V
G
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001099299
4392
468662
S2577
K
R
G
G
S
L
P
S
R
H
Q
I
V
G
S
Dog
Lupus familis
XP_535371
2720
290354
E1007
Q
E
I
V
R
C
D
E
R
G
S
V
G
T
S
Cat
Felis silvestris
Mouse
Mus musculus
Q05793
3707
398275
S1994
T
W
R
K
E
G
G
S
L
P
F
R
H
Q
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518520
1150
124768
Chicken
Gallus gallus
NP_001001876
4071
432826
L2358
S
E
G
Q
T
L
D
L
D
C
I
V
A
S
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001120939
3407
371297
S1694
I
E
E
P
K
A
Q
S
V
R
V
G
S
T
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001027037
4179
461773
T2420
S
I
Q
K
P
E
I
T
I
V
P
V
G
G
S
Honey Bee
Apis mellifera
XP_393220
3382
373579
L1669
V
D
D
N
H
G
L
L
V
I
R
D
V
K
V
Nematode Worm
Caenorhab. elegans
Q06561
3375
369033
I1662
L
T
D
E
G
D
Y
I
C
T
A
R
D
P
D
Sea Urchin
Strong. purpuratus
XP_001186142
2326
251883
E612
E
I
C
A
P
G
Y
E
G
N
P
T
Q
P
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.8
51.7
N.A.
72.7
N.A.
N.A.
20.8
58.1
N.A.
45.2
N.A.
22.1
25.7
24.2
24.2
Protein Similarity:
100
N.A.
98.6
54.6
N.A.
77.8
N.A.
N.A.
23.2
69.8
N.A.
57.4
N.A.
35.9
39.4
37.9
34.7
P-Site Identity:
100
N.A.
100
13.3
N.A.
6.6
N.A.
N.A.
0
13.3
N.A.
6.6
N.A.
13.3
6.6
0
0
P-Site Similarity:
100
N.A.
100
26.6
N.A.
13.3
N.A.
N.A.
0
26.6
N.A.
6.6
N.A.
26.6
13.3
0
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
10
0
0
0
0
10
0
10
0
10
% A
% Cys:
0
0
10
0
0
10
0
0
10
10
0
0
0
0
0
% C
% Asp:
0
10
19
0
0
10
19
0
10
0
0
10
10
0
10
% D
% Glu:
10
28
10
10
10
10
0
19
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
28
19
10
28
10
0
10
10
0
10
19
28
10
% G
% His:
0
0
0
0
10
0
0
0
0
19
0
0
10
0
0
% H
% Ile:
10
19
10
0
0
0
10
10
10
10
10
19
0
0
0
% I
% Lys:
19
0
0
19
10
0
0
0
0
0
0
0
0
10
0
% K
% Leu:
10
0
0
0
0
28
10
19
10
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
10
19
0
19
0
0
10
19
0
0
19
0
% P
% Gln:
10
0
10
10
0
0
10
0
0
0
19
0
10
10
10
% Q
% Arg:
0
19
10
0
10
0
0
0
28
10
10
19
0
0
0
% R
% Ser:
19
0
0
0
19
0
0
37
0
0
10
0
10
10
37
% S
% Thr:
10
10
0
0
10
0
0
10
0
10
0
10
0
19
0
% T
% Val:
10
0
0
10
0
0
0
0
19
10
10
28
28
0
19
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
19
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _