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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HSPG2 All Species: 9.7
Human Site: T3929 Identified Species: 21.33
UniProt: P98160 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P98160 NP_005520.4 4391 468798 T3929 E E G V T V T T P S L S G A G
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001099299 4392 468662 T3930 E E G V T V T T P S L S G A G
Dog Lupus familis XP_535371 2720 290354 L2298 H V A E G Q T L D L N C V V P
Cat Felis silvestris
Mouse Mus musculus Q05793 3707 398275 F3285 E P N G I L L F S G G K S G P
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518520 1150 124768 S728 Q E S L F S L S D A V G T H S
Chicken Gallus gallus NP_001001876 4071 432826 R3649 V E A E F L P R A P D G L L L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001120939 3407 371297 S2985 P D G L M F F S G G K K M K V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001027037 4179 461773 L3733 E I L N E H S L N F K G N S F
Honey Bee Apis mellifera XP_393220 3382 373579 I2960 V N G E P T V I G K S P G S D
Nematode Worm Caenorhab. elegans Q06561 3375 369033 S2953 V D L Q N L S S S G D I S S C
Sea Urchin Strong. purpuratus XP_001186142 2326 251883 T1903 C P F G F T G T N C E E V A N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 97.8 51.7 N.A. 72.7 N.A. N.A. 20.8 58.1 N.A. 45.2 N.A. 22.1 25.7 24.2 24.2
Protein Similarity: 100 N.A. 98.6 54.6 N.A. 77.8 N.A. N.A. 23.2 69.8 N.A. 57.4 N.A. 35.9 39.4 37.9 34.7
P-Site Identity: 100 N.A. 100 6.6 N.A. 6.6 N.A. N.A. 6.6 6.6 N.A. 6.6 N.A. 6.6 13.3 0 13.3
P-Site Similarity: 100 N.A. 100 6.6 N.A. 13.3 N.A. N.A. 40 13.3 N.A. 26.6 N.A. 20 20 33.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 19 0 0 0 0 0 10 10 0 0 0 28 0 % A
% Cys: 10 0 0 0 0 0 0 0 0 10 0 10 0 0 10 % C
% Asp: 0 19 0 0 0 0 0 0 19 0 19 0 0 0 10 % D
% Glu: 37 37 0 28 10 0 0 0 0 0 10 10 0 0 0 % E
% Phe: 0 0 10 0 28 10 10 10 0 10 0 0 0 0 10 % F
% Gly: 0 0 37 19 10 0 10 0 19 28 10 28 28 10 19 % G
% His: 10 0 0 0 0 10 0 0 0 0 0 0 0 10 0 % H
% Ile: 0 10 0 0 10 0 0 10 0 0 0 10 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 10 19 19 0 10 0 % K
% Leu: 0 0 19 19 0 28 19 19 0 10 19 0 10 10 10 % L
% Met: 0 0 0 0 10 0 0 0 0 0 0 0 10 0 0 % M
% Asn: 0 10 10 10 10 0 0 0 19 0 10 0 10 0 10 % N
% Pro: 10 19 0 0 10 0 10 0 19 10 0 10 0 0 19 % P
% Gln: 10 0 0 10 0 10 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % R
% Ser: 0 0 10 0 0 10 19 28 19 19 10 19 19 28 10 % S
% Thr: 0 0 0 0 19 19 28 28 0 0 0 0 10 0 0 % T
% Val: 28 10 0 19 0 19 10 0 0 0 10 0 19 10 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _