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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRP2
All Species:
22.42
Human Site:
S4503
Identified Species:
49.33
UniProt:
P98164
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P98164
NP_004516.2
4655
521958
S4503
P
E
T
A
I
D
R
S
M
A
M
S
E
D
F
Chimpanzee
Pan troglodytes
XP_515882
4655
521864
S4503
P
E
T
A
I
D
R
S
M
A
M
S
E
D
F
Rhesus Macaque
Macaca mulatta
XP_001104179
4667
522944
S4515
P
E
T
S
I
D
R
S
M
A
M
S
E
D
F
Dog
Lupus familis
XP_535946
4646
520610
S4496
P
E
S
A
I
D
R
S
M
V
M
S
E
N
F
Cat
Felis silvestris
Mouse
Mus musculus
A2ARV4
4660
519190
S4504
P
E
T
I
I
D
R
S
M
A
M
N
E
Q
F
Rat
Rattus norvegicus
P98158
4660
519258
S4504
P
E
T
I
I
D
R
S
M
A
M
N
E
H
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P98157
4543
507114
T4392
T
C
S
I
S
D
K
T
Q
L
P
E
C
L
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919788
4672
521726
M4519
V
S
F
I
D
R
A
M
Q
L
D
E
N
F
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001096924
4769
530147
M4620
P
F
G
K
L
A
R
M
P
A
M
T
S
S
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q04833
4753
526406
K4605
R
R
Q
L
L
F
K
K
N
E
A
A
D
G
S
Sea Urchin
Strong. purpuratus
XP_787118
4478
501013
L4330
L
N
Q
S
C
V
V
L
T
D
G
I
D
C
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
97.3
79.1
N.A.
76.8
76.5
N.A.
N.A.
37.1
N.A.
65.6
N.A.
41.8
N.A.
35.2
34.4
Protein Similarity:
100
99.7
98.5
88
N.A.
87.6
87.5
N.A.
N.A.
54.2
N.A.
80
N.A.
58.6
N.A.
53.4
51.8
P-Site Identity:
100
100
93.3
80
N.A.
80
80
N.A.
N.A.
6.6
N.A.
0
N.A.
26.6
N.A.
0
0
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
N.A.
26.6
N.A.
0
N.A.
40
N.A.
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
28
0
10
10
0
0
55
10
10
0
0
10
% A
% Cys:
0
10
0
0
10
0
0
0
0
0
0
0
10
10
10
% C
% Asp:
0
0
0
0
10
64
0
0
0
10
10
0
19
28
0
% D
% Glu:
0
55
0
0
0
0
0
0
0
10
0
19
55
0
0
% E
% Phe:
0
10
10
0
0
10
0
0
0
0
0
0
0
10
55
% F
% Gly:
0
0
10
0
0
0
0
0
0
0
10
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
0
37
55
0
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
0
0
10
0
0
19
10
0
0
0
0
0
0
0
% K
% Leu:
10
0
0
10
19
0
0
10
0
19
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
19
55
0
64
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
10
0
0
19
10
10
0
% N
% Pro:
64
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% P
% Gln:
0
0
19
0
0
0
0
0
19
0
0
0
0
10
10
% Q
% Arg:
10
10
0
0
0
10
64
0
0
0
0
0
0
0
10
% R
% Ser:
0
10
19
19
10
0
0
55
0
0
0
37
10
10
10
% S
% Thr:
10
0
46
0
0
0
0
10
10
0
0
10
0
0
0
% T
% Val:
10
0
0
0
0
10
10
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _