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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRP2
All Species:
11.21
Human Site:
S4569
Identified Species:
24.67
UniProt:
P98164
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P98164
NP_004516.2
4655
521958
S4569
V
P
E
T
N
P
T
S
P
A
A
D
G
T
Q
Chimpanzee
Pan troglodytes
XP_515882
4655
521864
S4569
V
P
E
T
N
P
T
S
P
A
A
D
G
T
Q
Rhesus Macaque
Macaca mulatta
XP_001104179
4667
522944
S4581
V
P
E
T
S
P
T
S
P
A
A
D
G
T
Q
Dog
Lupus familis
XP_535946
4646
520610
P4560
E
I
A
P
D
T
K
P
T
S
P
S
A
D
G
Cat
Felis silvestris
Mouse
Mus musculus
A2ARV4
4660
519190
K4574
S
E
I
V
P
E
P
K
P
A
S
P
G
A
D
Rat
Rattus norvegicus
P98158
4660
519258
K4574
S
E
I
V
P
E
P
K
P
A
S
P
G
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P98157
4543
507114
Q4456
G
A
K
G
F
Q
H
Q
R
M
T
N
G
A
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919788
4672
521726
Q4586
A
V
E
V
K
S
E
Q
V
E
E
K
N
T
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001096924
4769
530147
V4682
A
N
P
M
Y
D
A
V
Q
S
G
T
T
A
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q04833
4753
526406
S4667
L
E
D
V
D
M
S
S
P
P
P
S
N
D
Q
Sea Urchin
Strong. purpuratus
XP_787118
4478
501013
E4392
G
F
A
H
R
R
I
E
S
E
E
D
M
E
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
97.3
79.1
N.A.
76.8
76.5
N.A.
N.A.
37.1
N.A.
65.6
N.A.
41.8
N.A.
35.2
34.4
Protein Similarity:
100
99.7
98.5
88
N.A.
87.6
87.5
N.A.
N.A.
54.2
N.A.
80
N.A.
58.6
N.A.
53.4
51.8
P-Site Identity:
100
100
93.3
0
N.A.
20
20
N.A.
N.A.
6.6
N.A.
20
N.A.
0
N.A.
20
6.6
P-Site Similarity:
100
100
100
13.3
N.A.
26.6
26.6
N.A.
N.A.
20
N.A.
20
N.A.
6.6
N.A.
46.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
10
19
0
0
0
10
0
0
46
28
0
10
37
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
19
10
0
0
0
0
0
37
0
19
28
% D
% Glu:
10
28
37
0
0
19
10
10
0
19
19
0
0
10
0
% E
% Phe:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
19
0
0
10
0
0
0
0
0
0
10
0
55
0
10
% G
% His:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
19
0
0
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
0
10
0
10
19
0
0
0
10
0
0
0
% K
% Leu:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
10
0
10
0
0
0
10
0
0
10
0
10
% M
% Asn:
0
10
0
0
19
0
0
0
0
0
0
10
19
0
0
% N
% Pro:
0
28
10
10
19
28
19
10
55
10
19
19
0
0
0
% P
% Gln:
0
0
0
0
0
10
0
19
10
0
0
0
0
0
46
% Q
% Arg:
0
0
0
0
10
10
0
0
10
0
0
0
0
0
0
% R
% Ser:
19
0
0
0
10
10
10
37
10
19
19
19
0
0
0
% S
% Thr:
0
0
0
28
0
10
28
0
10
0
10
10
10
37
0
% T
% Val:
28
10
0
37
0
0
0
10
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _