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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRP2
All Species:
9.7
Human Site:
S4608
Identified Species:
21.33
UniProt:
P98164
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P98164
NP_004516.2
4655
521958
S4608
M
E
N
E
Q
K
E
S
V
A
A
T
P
P
P
Chimpanzee
Pan troglodytes
XP_515882
4655
521864
S4608
M
E
N
E
Q
K
E
S
V
A
A
A
P
P
P
Rhesus Macaque
Macaca mulatta
XP_001104179
4667
522944
T4620
M
E
N
E
Q
K
E
T
V
A
A
T
P
P
P
Dog
Lupus familis
XP_535946
4646
520610
K4599
A
E
M
E
N
E
Q
K
D
S
T
A
V
A
P
Cat
Felis silvestris
Mouse
Mus musculus
A2ARV4
4660
519190
Q4613
Y
A
E
M
D
T
E
Q
K
E
A
V
A
V
A
Rat
Rattus norvegicus
P98158
4660
519258
V4613
Y
A
E
M
D
S
E
V
K
D
A
V
A
V
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P98157
4543
507114
P4495
D
A
D
F
A
L
D
P
D
K
P
T
N
F
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919788
4672
521726
G4625
M
Q
D
E
Q
T
P
G
A
A
D
S
S
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001096924
4769
530147
T4721
H
H
A
G
G
S
F
T
E
P
A
S
A
I
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q04833
4753
526406
E4706
T
F
D
Q
D
E
I
E
L
K
T
A
D
E
I
Sea Urchin
Strong. purpuratus
XP_787118
4478
501013
A4431
F
T
V
R
D
H
K
A
R
T
N
F
T
N
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
97.3
79.1
N.A.
76.8
76.5
N.A.
N.A.
37.1
N.A.
65.6
N.A.
41.8
N.A.
35.2
34.4
Protein Similarity:
100
99.7
98.5
88
N.A.
87.6
87.5
N.A.
N.A.
54.2
N.A.
80
N.A.
58.6
N.A.
53.4
51.8
P-Site Identity:
100
93.3
93.3
20
N.A.
13.3
13.3
N.A.
N.A.
6.6
N.A.
26.6
N.A.
6.6
N.A.
0
6.6
P-Site Similarity:
100
93.3
100
40
N.A.
13.3
13.3
N.A.
N.A.
20
N.A.
46.6
N.A.
20
N.A.
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
28
10
0
10
0
0
10
10
37
55
28
28
10
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
28
0
37
0
10
0
19
10
10
0
10
0
0
% D
% Glu:
0
37
19
46
0
19
46
10
10
10
0
0
0
10
0
% E
% Phe:
10
10
0
10
0
0
10
0
0
0
0
10
0
10
0
% F
% Gly:
0
0
0
10
10
0
0
10
0
0
0
0
0
0
0
% G
% His:
10
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
19
% I
% Lys:
0
0
0
0
0
28
10
10
19
19
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% L
% Met:
37
0
10
19
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
28
0
10
0
0
0
0
0
10
0
10
10
0
% N
% Pro:
0
0
0
0
0
0
10
10
0
10
10
0
28
28
46
% P
% Gln:
0
10
0
10
37
0
10
10
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
19
0
19
0
10
0
19
10
10
0
% S
% Thr:
10
10
0
0
0
19
0
19
0
10
19
28
10
0
19
% T
% Val:
0
0
10
0
0
0
0
10
28
0
0
19
10
19
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
19
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _