KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRP2
All Species:
14.24
Human Site:
T4591
Identified Species:
31.33
UniProt:
P98164
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P98164
NP_004516.2
4655
521958
T4591
K
R
K
S
K
Q
T
T
N
F
E
N
P
I
Y
Chimpanzee
Pan troglodytes
XP_515882
4655
521864
T4591
K
R
K
A
K
Q
T
T
N
F
E
N
P
I
Y
Rhesus Macaque
Macaca mulatta
XP_001104179
4667
522944
T4603
K
R
K
T
K
Q
T
T
N
F
E
N
P
I
Y
Dog
Lupus familis
XP_535946
4646
520610
P4582
I
F
K
R
K
L
K
P
T
T
N
F
E
N
P
Cat
Felis silvestris
Mouse
Mus musculus
A2ARV4
4660
519190
K4596
N
I
F
K
R
K
P
K
Q
T
T
N
F
E
N
Rat
Rattus norvegicus
P98158
4660
519258
K4596
N
I
F
K
R
K
P
K
Q
T
T
N
F
E
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P98157
4543
507114
E4478
T
Y
K
M
Y
E
G
E
P
D
D
D
V
G
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919788
4672
521726
T4608
K
R
K
L
K
P
S
T
T
F
E
N
P
T
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001096924
4769
530147
E4704
G
I
Y
D
V
P
G
E
P
S
A
K
V
K
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q04833
4753
526406
T4689
M
S
P
N
R
P
S
T
S
A
A
S
S
F
V
Sea Urchin
Strong. purpuratus
XP_787118
4478
501013
E4414
S
R
Q
V
N
E
E
E
E
G
A
D
G
M
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
97.3
79.1
N.A.
76.8
76.5
N.A.
N.A.
37.1
N.A.
65.6
N.A.
41.8
N.A.
35.2
34.4
Protein Similarity:
100
99.7
98.5
88
N.A.
87.6
87.5
N.A.
N.A.
54.2
N.A.
80
N.A.
58.6
N.A.
53.4
51.8
P-Site Identity:
100
93.3
93.3
13.3
N.A.
6.6
6.6
N.A.
N.A.
6.6
N.A.
66.6
N.A.
0
N.A.
6.6
6.6
P-Site Similarity:
100
100
100
13.3
N.A.
20
20
N.A.
N.A.
26.6
N.A.
73.3
N.A.
0
N.A.
40
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
0
10
28
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
10
10
19
0
0
10
% D
% Glu:
0
0
0
0
0
19
10
28
10
0
37
0
10
19
10
% E
% Phe:
0
10
19
0
0
0
0
0
0
37
0
10
19
10
0
% F
% Gly:
10
0
0
0
0
0
19
0
0
10
0
0
10
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
28
0
0
0
0
0
0
0
0
0
0
0
28
0
% I
% Lys:
37
0
55
19
46
19
10
19
0
0
0
10
0
10
0
% K
% Leu:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% L
% Met:
10
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
19
0
0
10
10
0
0
0
28
0
10
55
0
10
19
% N
% Pro:
0
0
10
0
0
28
19
10
19
0
0
0
37
0
10
% P
% Gln:
0
0
10
0
0
28
0
0
19
0
0
0
0
0
0
% Q
% Arg:
0
46
0
10
28
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
10
0
10
0
0
19
0
10
10
0
10
10
0
10
% S
% Thr:
10
0
0
10
0
0
28
46
19
28
19
0
0
10
0
% T
% Val:
0
0
0
10
10
0
0
0
0
0
0
0
19
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
10
0
10
0
0
0
0
0
0
0
0
0
37
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _