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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRP2
All Species:
22.42
Human Site:
Y1856
Identified Species:
49.33
UniProt:
P98164
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P98164
NP_004516.2
4655
521958
Y1856
T
L
H
G
D
I
R
Y
R
K
T
L
I
A
N
Chimpanzee
Pan troglodytes
XP_515882
4655
521864
Y1856
T
L
H
G
D
I
R
Y
R
K
T
L
I
A
N
Rhesus Macaque
Macaca mulatta
XP_001104179
4667
522944
Y1868
T
L
H
G
D
I
R
Y
R
K
T
L
I
A
N
Dog
Lupus familis
XP_535946
4646
520610
Y1854
K
L
Q
G
D
V
R
Y
R
K
T
L
I
T
N
Cat
Felis silvestris
Mouse
Mus musculus
A2ARV4
4660
519190
Y1857
T
L
R
G
D
T
R
Y
G
K
T
L
I
T
N
Rat
Rattus norvegicus
P98158
4660
519258
Y1857
T
L
K
G
D
T
R
Y
G
K
T
L
I
A
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P98157
4543
507114
V1818
N
K
K
D
G
T
E
V
T
V
L
R
N
S
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919788
4672
521726
F1874
R
L
K
G
E
I
Q
F
R
K
T
L
I
T
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001096924
4769
530147
Y1985
R
V
D
G
K
Q
K
Y
R
T
I
I
L
A
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q04833
4753
526406
Q1915
I
I
R
T
Q
G
K
Q
Y
R
S
V
I
L
S
Sea Urchin
Strong. purpuratus
XP_787118
4478
501013
H1807
V
H
K
N
D
S
D
H
I
N
I
L
R
R
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
97.3
79.1
N.A.
76.8
76.5
N.A.
N.A.
37.1
N.A.
65.6
N.A.
41.8
N.A.
35.2
34.4
Protein Similarity:
100
99.7
98.5
88
N.A.
87.6
87.5
N.A.
N.A.
54.2
N.A.
80
N.A.
58.6
N.A.
53.4
51.8
P-Site Identity:
100
100
100
73.3
N.A.
73.3
80
N.A.
N.A.
0
N.A.
60
N.A.
33.3
N.A.
6.6
13.3
P-Site Similarity:
100
100
100
80
N.A.
73.3
80
N.A.
N.A.
6.6
N.A.
80
N.A.
60
N.A.
46.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
46
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
10
64
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
73
10
10
0
0
19
0
0
0
0
0
0
% G
% His:
0
10
28
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
10
10
0
0
0
37
0
0
10
0
19
10
73
0
0
% I
% Lys:
10
10
37
0
10
0
19
0
0
64
0
0
0
0
10
% K
% Leu:
0
64
0
0
0
0
0
0
0
0
10
73
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
10
0
0
0
0
0
10
0
0
10
0
73
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
0
10
10
10
10
0
0
0
0
0
0
0
% Q
% Arg:
19
0
19
0
0
0
55
0
55
10
0
10
10
10
0
% R
% Ser:
0
0
0
0
0
10
0
0
0
0
10
0
0
10
10
% S
% Thr:
46
0
0
10
0
28
0
0
10
10
64
0
0
28
10
% T
% Val:
10
10
0
0
0
10
0
10
0
10
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
64
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _