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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRP2
All Species:
28.48
Human Site:
Y4028
Identified Species:
62.67
UniProt:
P98164
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P98164
NP_004516.2
4655
521958
Y4028
C
R
N
T
K
G
S
Y
E
C
V
C
A
D
G
Chimpanzee
Pan troglodytes
XP_515882
4655
521864
Y4028
C
R
N
T
K
G
S
Y
E
C
V
C
A
D
G
Rhesus Macaque
Macaca mulatta
XP_001104179
4667
522944
Y4040
C
R
N
T
K
G
S
Y
E
C
V
C
A
D
G
Dog
Lupus familis
XP_535946
4646
520610
Y4022
C
Q
N
T
K
G
S
Y
E
C
S
C
A
E
G
Cat
Felis silvestris
Mouse
Mus musculus
A2ARV4
4660
519190
Y4030
C
R
N
S
K
G
S
Y
E
C
F
C
V
D
G
Rat
Rattus norvegicus
P98158
4660
519258
Y4030
C
R
N
S
K
G
S
Y
E
C
F
C
V
D
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P98157
4543
507114
C3925
H
T
G
R
I
S
Y
C
E
L
P
A
S
S
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919788
4672
521726
Y4044
C
K
N
T
K
G
S
Y
E
C
F
C
A
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001096924
4769
530147
S4175
L
T
R
Q
H
T
C
S
H
Q
C
H
N
L
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q04833
4753
526406
Y4153
C
L
N
T
K
G
S
Y
L
C
R
C
H
E
D
Sea Urchin
Strong. purpuratus
XP_787118
4478
501013
L3867
H
N
S
T
G
Y
R
L
Y
Q
A
P
L
N
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
97.3
79.1
N.A.
76.8
76.5
N.A.
N.A.
37.1
N.A.
65.6
N.A.
41.8
N.A.
35.2
34.4
Protein Similarity:
100
99.7
98.5
88
N.A.
87.6
87.5
N.A.
N.A.
54.2
N.A.
80
N.A.
58.6
N.A.
53.4
51.8
P-Site Identity:
100
100
100
80
N.A.
80
80
N.A.
N.A.
6.6
N.A.
80
N.A.
0
N.A.
60
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
N.A.
13.3
N.A.
93.3
N.A.
0
N.A.
66.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
10
10
46
0
10
% A
% Cys:
73
0
0
0
0
0
10
10
0
73
10
73
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
46
10
% D
% Glu:
0
0
0
0
0
0
0
0
73
0
0
0
0
28
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
28
0
0
0
0
% F
% Gly:
0
0
10
0
10
73
0
0
0
0
0
0
0
0
64
% G
% His:
19
0
0
0
10
0
0
0
10
0
0
10
10
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
73
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
10
0
0
0
0
0
10
10
10
0
0
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
73
0
0
0
0
0
0
0
0
0
10
10
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% P
% Gln:
0
10
0
10
0
0
0
0
0
19
0
0
0
0
0
% Q
% Arg:
0
46
10
10
0
0
10
0
0
0
10
0
0
0
0
% R
% Ser:
0
0
10
19
0
10
73
10
0
0
10
0
10
10
10
% S
% Thr:
0
19
0
64
0
10
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
28
0
19
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
10
73
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _