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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZXDB All Species: 12.42
Human Site: S591 Identified Species: 30.37
UniProt: P98169 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P98169 NP_009088.1 803 84792 S591 A A N S L T P S S E L T S Q R
Chimpanzee Pan troglodytes XP_001149537 809 85518 S597 A A N S L T P S S E L T S Q R
Rhesus Macaque Macaca mulatta XP_001096238 798 84756 P586 E A A N S L T P S S E L T S Q
Dog Lupus familis XP_549032 869 92225 S657 A A N S L T P S S E L T S Q G
Cat Felis silvestris
Mouse Mus musculus A2CE44 873 90358 S661 A N S L T P S S E L T S P G Q
Rat Rattus norvegicus Q5XIU2 638 68981 K427 N H C G K T Y K Q I S T L A M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519008 546 58149 L335 Q R P F K C P L D G C G W S F
Chicken Gallus gallus
Frog Xenopus laevis Q91853 565 61399 S353 G E R P Y Y C S E P G C G R A
Zebra Danio Brachydanio rerio Q1LYE3 623 67910 C412 T P C K P Y N C N H C G K T Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001120050 1394 158717 T1154 I N V A C L N T S I I K E K T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98 95.5 81.5 N.A. 76.6 21.2 N.A. 39.8 N.A. 24.5 20.9 N.A. N.A. 20.2 N.A. N.A.
Protein Similarity: 100 98.1 96.6 84.1 N.A. 80.9 36.3 N.A. 43.9 N.A. 36.1 35.4 N.A. N.A. 32 N.A. N.A.
P-Site Identity: 100 100 13.3 93.3 N.A. 13.3 13.3 N.A. 6.6 N.A. 6.6 0 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 100 100 33.3 93.3 N.A. 33.3 13.3 N.A. 6.6 N.A. 13.3 6.6 N.A. N.A. 33.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 40 40 10 10 0 0 0 0 0 0 0 0 0 10 10 % A
% Cys: 0 0 20 0 10 10 10 10 0 0 20 10 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % D
% Glu: 10 10 0 0 0 0 0 0 20 30 10 0 10 0 0 % E
% Phe: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 10 % F
% Gly: 10 0 0 10 0 0 0 0 0 10 10 20 10 10 10 % G
% His: 0 10 0 0 0 0 0 0 0 10 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 0 0 0 0 20 10 0 0 0 0 % I
% Lys: 0 0 0 10 20 0 0 10 0 0 0 10 10 10 0 % K
% Leu: 0 0 0 10 30 20 0 10 0 10 30 10 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 10 20 30 10 0 0 20 0 10 0 0 0 0 0 0 % N
% Pro: 0 10 10 10 10 10 40 10 0 10 0 0 10 0 0 % P
% Gln: 10 0 0 0 0 0 0 0 10 0 0 0 0 30 20 % Q
% Arg: 0 10 10 0 0 0 0 0 0 0 0 0 0 10 20 % R
% Ser: 0 0 10 30 10 0 10 50 50 10 10 10 30 20 0 % S
% Thr: 10 0 0 0 10 40 10 10 0 0 10 40 10 10 10 % T
% Val: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % W
% Tyr: 0 0 0 0 10 20 10 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _