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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARHGAP4
All Species:
6.06
Human Site:
S304
Identified Species:
22.22
UniProt:
P98171
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P98171
NP_001657.3
946
105026
S304
S
Q
V
Q
G
L
G
S
L
E
E
A
V
E
A
Chimpanzee
Pan troglodytes
XP_509190
1085
124290
I301
S
R
H
E
G
L
D
I
I
E
N
A
V
D
N
Rhesus Macaque
Macaca mulatta
XP_001097218
1099
124453
V301
S
R
H
E
G
L
D
V
I
E
N
A
V
D
N
Dog
Lupus familis
XP_549365
938
102803
S292
S
Q
M
Q
G
L
G
S
L
E
E
A
V
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q812A2
1099
124401
V301
S
R
H
E
G
L
D
V
I
E
N
A
V
D
N
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001025775
853
98054
S286
R
T
F
R
T
Y
L
S
A
E
Y
N
L
E
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6PCS4
1337
147647
K368
A
R
L
L
K
M
Q
K
R
E
E
Y
E
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.9
42.3
86.3
N.A.
42.3
N.A.
N.A.
N.A.
45.9
N.A.
21
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
59.1
59.1
89.7
N.A.
59.5
N.A.
N.A.
N.A.
63.7
N.A.
36.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
40
40
93.3
N.A.
40
N.A.
N.A.
N.A.
20
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
66.6
66.6
100
N.A.
66.6
N.A.
N.A.
N.A.
33.3
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
0
0
0
0
0
0
15
0
0
72
0
0
43
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
43
0
0
0
0
0
0
43
0
% D
% Glu:
0
0
0
43
0
0
0
0
0
100
43
0
15
43
0
% E
% Phe:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
72
0
29
0
0
0
0
0
0
0
0
% G
% His:
0
0
43
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
15
43
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
15
0
0
15
0
0
0
0
0
15
0
% K
% Leu:
0
0
15
15
0
72
15
0
29
0
0
0
15
0
0
% L
% Met:
0
0
15
0
0
15
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
43
15
0
0
43
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
29
0
29
0
0
15
0
0
0
0
0
0
0
0
% Q
% Arg:
15
58
0
15
0
0
0
0
15
0
0
0
0
0
0
% R
% Ser:
72
0
0
0
0
0
0
43
0
0
0
0
0
0
0
% S
% Thr:
0
15
0
0
15
0
0
0
0
0
0
0
0
0
15
% T
% Val:
0
0
15
0
0
0
0
29
0
0
0
0
72
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
15
0
0
0
0
15
15
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _