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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EFNB1 All Species: 27.58
Human Site: Y343 Identified Species: 67.41
UniProt: P98172 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P98172 NP_004420.1 346 38007 Y343 P Q S P A N I Y Y K V _ _ _ _
Chimpanzee Pan troglodytes XP_529024 368 39511 S359 T P L T P G F S A L L F C C H
Rhesus Macaque Macaca mulatta XP_001082851 738 79692 Y735 P Q S P A N I Y Y K V _ _ _ _
Dog Lupus familis XP_849150 317 34681 C314 W T T E N N Y C P H Y _ _ _ _
Cat Felis silvestris
Mouse Mus musculus P52795 345 37841 Y342 P Q S P A N I Y Y K V _ _ _ _
Rat Rattus norvegicus P52796 345 37933 Y342 P Q S P A N I Y Y K V _ _ _ _
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512874 312 34324
Chicken Gallus gallus O73612 334 36840 Y331 P Q S P A N I Y Y K V _ _ _ _
Frog Xenopus laevis O13097 329 36574 Y326 P Q S P A N I Y Y K V _ _ _ _
Zebra Danio Brachydanio rerio O73874 332 36706 Y329 P Q S P A N I Y Y K V _ _ _ _
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 75.5 44.3 87.8 N.A. 95.6 94.8 N.A. 51.4 77.4 72.5 52.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 79.3 44.5 88.7 N.A. 96.8 96.5 N.A. 67 87.8 85.2 66.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 100 9 N.A. 100 100 N.A. 0 100 100 100 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 6.6 100 18.1 N.A. 100 100 N.A. 0 100 100 100 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 70 0 0 0 10 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 10 0 0 0 0 10 10 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 10 0 0 0 0 10 0 0 0 % F
% Gly: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 10 % H
% Ile: 0 0 0 0 0 0 70 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 70 0 0 0 0 0 % K
% Leu: 0 0 10 0 0 0 0 0 0 10 10 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 10 80 0 0 0 0 0 0 0 0 0 % N
% Pro: 70 10 0 70 10 0 0 0 10 0 0 0 0 0 0 % P
% Gln: 0 70 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 70 0 0 0 0 10 0 0 0 0 0 0 0 % S
% Thr: 10 10 10 10 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 70 0 0 0 0 % V
% Trp: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 70 70 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 80 80 80 80 % _