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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FGD1
All Species:
11.82
Human Site:
S538
Identified Species:
37.14
UniProt:
P98174
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P98174
NP_004454.2
961
106561
S538
L
L
K
L
P
H
G
S
P
D
S
K
D
A
Q
Chimpanzee
Pan troglodytes
XP_520721
853
95715
N461
P
P
D
S
L
D
W
N
D
A
K
K
S
L
E
Rhesus Macaque
Macaca mulatta
XP_001084734
931
103917
S535
L
R
K
L
P
P
D
S
L
D
W
N
D
A
K
Dog
Lupus familis
XP_549021
960
106256
S537
L
L
K
L
P
H
G
S
P
D
S
K
D
A
Q
Cat
Felis silvestris
Mouse
Mus musculus
P52734
960
106459
S537
L
L
K
L
P
H
G
S
P
D
S
K
D
A
Q
Rat
Rattus norvegicus
O88387
766
86435
N374
S
P
D
A
P
D
W
N
D
A
K
K
S
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416365
757
86249
D365
Q
D
S
L
D
W
K
D
A
E
K
S
L
E
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_688794
945
105983
A533
L
H
R
L
P
E
D
A
D
D
F
K
D
A
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.3
41.6
95.8
N.A.
94.6
41.8
N.A.
N.A.
42.7
N.A.
57.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
58.3
59.3
96.5
N.A.
95.9
57.7
N.A.
N.A.
57.7
N.A.
67.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
53.3
100
N.A.
100
13.3
N.A.
N.A.
6.6
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
60
100
N.A.
100
26.6
N.A.
N.A.
13.3
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
13
0
0
0
13
13
25
0
0
0
63
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
13
25
0
13
25
25
13
38
63
0
0
63
0
0
% D
% Glu:
0
0
0
0
0
13
0
0
0
13
0
0
0
13
25
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
38
0
0
0
0
0
0
0
0
% G
% His:
0
13
0
0
0
38
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% I
% Lys:
0
0
50
0
0
0
13
0
0
0
38
75
0
0
13
% K
% Leu:
63
38
0
75
13
0
0
0
13
0
0
0
13
25
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
25
0
0
0
13
0
0
0
% N
% Pro:
13
25
0
0
75
13
0
0
38
0
0
0
0
0
0
% P
% Gln:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
50
% Q
% Arg:
0
13
13
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
13
0
13
13
0
0
0
50
0
0
38
13
25
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
13
25
0
0
0
13
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _