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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FOXO4
All Species:
13.94
Human Site:
T227
Identified Species:
34.07
UniProt:
P98177
Number Species:
9
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P98177
NP_005929.2
505
53684
T227
P
A
P
P
E
G
A
T
P
T
S
P
V
G
H
Chimpanzee
Pan troglodytes
XP_001135016
505
53494
T227
P
A
P
P
E
G
A
T
P
T
S
P
V
G
H
Rhesus Macaque
Macaca mulatta
XP_001088437
860
91177
D491
S
G
Q
E
G
A
G
D
S
P
G
S
Q
F
S
Dog
Lupus familis
XP_549066
509
54008
P231
A
P
S
E
G
A
T
P
T
S
P
V
G
H
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVH3
505
53631
T227
P
A
P
P
E
G
A
T
P
R
S
P
L
G
H
Rat
Rattus norvegicus
NP_001100413
505
53925
T227
P
A
P
P
E
G
A
T
P
R
S
P
L
G
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_426261
470
50115
Y202
E
L
L
P
S
M
V
Y
S
S
A
S
S
N
V
Frog
Xenopus laevis
Q6EUW1
657
70366
D268
A
S
S
D
A
T
D
D
S
P
S
Q
L
S
K
Zebra Danio
Brachydanio rerio
XP_692168
613
64303
D313
M
E
E
L
D
L
I
D
G
L
T
L
M
T
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q95V55
613
67394
Q317
T
L
C
N
Q
Q
Q
Q
G
F
S
A
A
S
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
31.9
92.1
N.A.
88.5
88.3
N.A.
N.A.
53.4
37.9
44.2
N.A.
28.5
N.A.
N.A.
N.A.
Protein Similarity:
100
98.8
42
95
N.A.
93
92.4
N.A.
N.A.
63.5
52
56.2
N.A.
43.5
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
0
N.A.
86.6
86.6
N.A.
N.A.
6.6
6.6
0
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
0
6.6
N.A.
93.3
93.3
N.A.
N.A.
20
20
20
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
40
0
0
10
20
40
0
0
0
10
10
10
0
10
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
10
0
10
30
0
0
0
0
0
0
0
% D
% Glu:
10
10
10
20
40
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
10
% F
% Gly:
0
10
0
0
20
40
10
0
20
0
10
0
10
40
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
40
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% K
% Leu:
0
20
10
10
0
10
0
0
0
10
0
10
30
0
0
% L
% Met:
10
0
0
0
0
10
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% N
% Pro:
40
10
40
50
0
0
0
10
40
20
10
40
0
0
0
% P
% Gln:
0
0
10
0
10
10
10
10
0
0
0
10
10
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
20
0
0
0
0
0
% R
% Ser:
10
10
20
0
10
0
0
0
30
20
60
20
10
20
10
% S
% Thr:
10
0
0
0
0
10
10
40
10
20
10
0
0
10
0
% T
% Val:
0
0
0
0
0
0
10
0
0
0
0
10
20
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _