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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CYP4F8 All Species: 20
Human Site: S454 Identified Species: 73.33
UniProt: P98187 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P98187 NP_009184.1 520 59995 S454 P E N A Q K R S P M A F I P F
Chimpanzee Pan troglodytes XP_001172317 520 60040 S454 P E N A Q K R S P M A F I P F
Rhesus Macaque Macaca mulatta XP_001112044 520 60031 S454 P E N I Q K R S P M A F I P F
Dog Lupus familis XP_541983 540 62222 S470 P E I P Q K R S P L A F I P F
Cat Felis silvestris
Mouse Mus musculus Q9EP75 524 59782 S454 P E N I K D S S P L A F I P F
Rat Rattus norvegicus P33274 524 59850 S454 P E N I K D S S P L A F I P F
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q27589 501 57896 H435 D A D V P Q I H P Y A Y I P F
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 90.7 70.9 N.A. 74 73.8 N.A. N.A. N.A. N.A. N.A. N.A. 36.5 N.A. N.A. N.A.
Protein Similarity: 100 99 95.1 80.3 N.A. 84.9 85.5 N.A. N.A. N.A. N.A. N.A. N.A. 56.9 N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 80 N.A. 66.6 66.6 N.A. N.A. N.A. N.A. N.A. N.A. 33.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 86.6 N.A. 80 80 N.A. N.A. N.A. N.A. N.A. N.A. 53.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 15 0 29 0 0 0 0 0 0 100 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 15 0 15 0 0 29 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 86 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 86 0 0 100 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 15 0 0 0 0 0 0 0 % H
% Ile: 0 0 15 43 0 0 15 0 0 0 0 0 100 0 0 % I
% Lys: 0 0 0 0 29 58 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 43 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 43 0 0 0 0 0 % M
% Asn: 0 0 72 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 86 0 0 15 15 0 0 0 100 0 0 0 0 100 0 % P
% Gln: 0 0 0 0 58 15 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 58 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 29 86 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 15 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 15 0 15 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _