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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP4F8
All Species:
20
Human Site:
S454
Identified Species:
73.33
UniProt:
P98187
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P98187
NP_009184.1
520
59995
S454
P
E
N
A
Q
K
R
S
P
M
A
F
I
P
F
Chimpanzee
Pan troglodytes
XP_001172317
520
60040
S454
P
E
N
A
Q
K
R
S
P
M
A
F
I
P
F
Rhesus Macaque
Macaca mulatta
XP_001112044
520
60031
S454
P
E
N
I
Q
K
R
S
P
M
A
F
I
P
F
Dog
Lupus familis
XP_541983
540
62222
S470
P
E
I
P
Q
K
R
S
P
L
A
F
I
P
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9EP75
524
59782
S454
P
E
N
I
K
D
S
S
P
L
A
F
I
P
F
Rat
Rattus norvegicus
P33274
524
59850
S454
P
E
N
I
K
D
S
S
P
L
A
F
I
P
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27589
501
57896
H435
D
A
D
V
P
Q
I
H
P
Y
A
Y
I
P
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
90.7
70.9
N.A.
74
73.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
36.5
N.A.
N.A.
N.A.
Protein Similarity:
100
99
95.1
80.3
N.A.
84.9
85.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
56.9
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
80
N.A.
66.6
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
86.6
N.A.
80
80
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
29
0
0
0
0
0
0
100
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
0
15
0
0
29
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
86
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
86
0
0
100
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% H
% Ile:
0
0
15
43
0
0
15
0
0
0
0
0
100
0
0
% I
% Lys:
0
0
0
0
29
58
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
43
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
43
0
0
0
0
0
% M
% Asn:
0
0
72
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
86
0
0
15
15
0
0
0
100
0
0
0
0
100
0
% P
% Gln:
0
0
0
0
58
15
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
58
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
29
86
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
15
0
15
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _