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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP2C1
All Species:
43.33
Human Site:
S621
Identified Species:
73.33
UniProt:
P98194
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P98194
NP_001001485.1
919
100577
S621
V
A
V
F
Y
R
A
S
P
R
H
K
M
K
I
Chimpanzee
Pan troglodytes
XP_001146321
919
100531
S621
V
A
V
F
Y
R
A
S
P
R
H
K
M
K
I
Rhesus Macaque
Macaca mulatta
XP_001113277
1062
115777
S744
V
A
V
F
Y
R
A
S
P
R
H
K
M
K
I
Dog
Lupus familis
XP_863679
919
100526
S621
V
A
V
F
Y
R
A
S
P
R
H
K
M
K
I
Cat
Felis silvestris
Mouse
Mus musculus
Q80XR2
918
100283
S620
V
A
V
F
Y
R
A
S
P
R
H
K
M
K
I
Rat
Rattus norvegicus
Q64566
919
100482
S621
V
A
V
F
Y
R
A
S
P
R
H
K
M
K
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514390
1116
121140
S820
V
A
V
F
Y
R
A
S
P
R
H
K
L
K
I
Chicken
Gallus gallus
Q9YGL9
1042
115411
F676
A
C
R
E
A
R
C
F
A
R
V
E
P
A
H
Frog
Xenopus laevis
NP_001089971
916
100146
S622
V
S
V
F
Y
R
T
S
P
K
H
K
L
K
I
Zebra Danio
Brachydanio rerio
XP_695172
925
101428
S628
V
V
V
F
Y
R
A
S
P
R
H
K
L
K
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P22700
1020
111683
F676
A
V
A
R
S
R
L
F
S
R
V
E
P
Q
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001028821
912
100593
S616
V
T
I
F
Y
R
A
S
P
R
H
K
L
K
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92939
1061
116347
E708
G
L
L
F
S
R
A
E
P
K
H
K
Q
E
I
Baker's Yeast
Sacchar. cerevisiae
P13586
950
104552
T657
V
N
I
F
A
R
A
T
P
E
H
K
L
N
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
85.5
98.4
N.A.
96.5
97
N.A.
78.8
32.6
66.3
81
N.A.
32
N.A.
N.A.
64.9
Protein Similarity:
100
100
85.8
99.3
N.A.
98.1
98.4
N.A.
80.7
50
80.3
90.4
N.A.
51
N.A.
N.A.
79.7
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
13.3
73.3
86.6
N.A.
13.3
N.A.
N.A.
80
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
20
93.3
93.3
N.A.
26.6
N.A.
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.3
49.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.8
67.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
50
8
0
15
0
79
0
8
0
0
0
0
8
0
% A
% Cys:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
8
0
0
0
8
0
8
0
15
0
8
0
% E
% Phe:
0
0
0
86
0
0
0
15
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
86
0
0
0
15
% H
% Ile:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
86
% I
% Lys:
0
0
0
0
0
0
0
0
0
15
0
86
0
72
0
% K
% Leu:
0
8
8
0
0
0
8
0
0
0
0
0
36
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
43
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
86
0
0
0
15
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% Q
% Arg:
0
0
8
8
0
100
0
0
0
79
0
0
0
0
0
% R
% Ser:
0
8
0
0
15
0
0
72
8
0
0
0
0
0
0
% S
% Thr:
0
8
0
0
0
0
8
8
0
0
0
0
0
0
0
% T
% Val:
79
15
65
0
0
0
0
0
0
0
15
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
72
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _