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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP2C1 All Species: 27.58
Human Site: S769 Identified Species: 46.67
UniProt: P98194 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P98194 NP_001001485.1 919 100577 S769 P P R N W K D S I L T K N L I
Chimpanzee Pan troglodytes XP_001146321 919 100531 S769 P P R N W K D S I L T K N L I
Rhesus Macaque Macaca mulatta XP_001113277 1062 115777 S892 P P R N W K D S I L T K N L I
Dog Lupus familis XP_863679 919 100526 S769 P P R N W K D S I L T R N L I
Cat Felis silvestris
Mouse Mus musculus Q80XR2 918 100283 S768 P P R N W K D S I L T K N L I
Rat Rattus norvegicus Q64566 919 100482 S769 P P R N W K D S I L T K N L I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514390 1116 121140 N964 V I R K P P R N W K D S I L T
Chicken Gallus gallus Q9YGL9 1042 115411 Y858 A A T W W F L Y D A E G P Q V
Frog Xenopus laevis NP_001089971 916 100146 N766 A I K Q P P R N A K E S I L S
Zebra Danio Brachydanio rerio XP_695172 925 101428 S776 P P R N V R D S I I T R S L I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P22700 1020 111683 F858 A A A W W F V F S D E G P K L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_001028821 912 100593 Q760 V I R K P P R Q V R D P M I T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P92939 1061 116347 W911 S Y S Q L A H W G Q C S S W E
Baker's Yeast Sacchar. cerevisiae P13586 950 104552 R800 E V M K K P P R K R T D K I L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 85.5 98.4 N.A. 96.5 97 N.A. 78.8 32.6 66.3 81 N.A. 32 N.A. N.A. 64.9
Protein Similarity: 100 100 85.8 99.3 N.A. 98.1 98.4 N.A. 80.7 50 80.3 90.4 N.A. 51 N.A. N.A. 79.7
P-Site Identity: 100 100 100 93.3 N.A. 100 100 N.A. 13.3 6.6 6.6 66.6 N.A. 6.6 N.A. N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 20 13.3 20 93.3 N.A. 13.3 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. 31.3 49.3 N.A.
Protein Similarity: N.A. N.A. N.A. 50.8 67.4 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 22 15 8 0 0 8 0 0 8 8 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 50 0 8 8 15 8 0 0 0 % D
% Glu: 8 0 0 0 0 0 0 0 0 0 22 0 0 0 8 % E
% Phe: 0 0 0 0 0 15 0 8 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 8 0 0 15 0 0 0 % G
% His: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % H
% Ile: 0 22 0 0 0 0 0 0 50 8 0 0 15 15 50 % I
% Lys: 0 0 8 22 8 43 0 0 8 15 0 36 8 8 0 % K
% Leu: 0 0 0 0 8 0 8 0 0 43 0 0 0 65 15 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 0 0 0 50 0 0 0 15 0 0 0 0 43 0 0 % N
% Pro: 50 50 0 0 22 29 8 0 0 0 0 8 15 0 0 % P
% Gln: 0 0 0 15 0 0 0 8 0 8 0 0 0 8 0 % Q
% Arg: 0 0 65 0 0 8 22 8 0 15 0 15 0 0 0 % R
% Ser: 8 0 8 0 0 0 0 50 8 0 0 22 15 0 8 % S
% Thr: 0 0 8 0 0 0 0 0 0 0 58 0 0 0 15 % T
% Val: 15 8 0 0 8 0 8 0 8 0 0 0 0 0 8 % V
% Trp: 0 0 0 15 58 0 0 8 8 0 0 0 0 8 0 % W
% Tyr: 0 8 0 0 0 0 0 8 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _