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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP2C1 All Species: 32.73
Human Site: T503 Identified Species: 55.38
UniProt: P98194 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P98194 NP_001001485.1 919 100577 T503 K G Q T L T L T Q Q Q R D V Y
Chimpanzee Pan troglodytes XP_001146321 919 100531 T503 K G Q T L T L T Q Q Q R D V Y
Rhesus Macaque Macaca mulatta XP_001113277 1062 115777 T626 K G Q T L T L T Q Q Q R D V Y
Dog Lupus familis XP_863679 919 100526 T503 K G Q T L A L T Q Q Q R D L Y
Cat Felis silvestris
Mouse Mus musculus Q80XR2 918 100283 T502 K G Q T L A L T Q Q Q R D L Y
Rat Rattus norvegicus Q64566 919 100482 T503 K G Q T L A L T Q Q Q R D L Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514390 1116 121140 T702 K G Q T V A L T Q Q Q R D L Y
Chicken Gallus gallus Q9YGL9 1042 115411 T558 D W G M G T D T L R C L A L A
Frog Xenopus laevis NP_001089971 916 100146 T504 G G R S L P I T P Q Q K S L Y
Zebra Danio Brachydanio rerio XP_695172 925 101428 N510 K G V T M P L N N Q Q R D F Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P22700 1020 111683 T558 Q Y G T G R D T L R C L A L A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_001028821 912 100593 N498 E D R S E P L N K Q K I E E I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P92939 1061 116347 D590 A Y S D V P S D F A T Y D G S
Baker's Yeast Sacchar. cerevisiae P13586 950 104552 S539 T I N E C A N S M A S E G L R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 85.5 98.4 N.A. 96.5 97 N.A. 78.8 32.6 66.3 81 N.A. 32 N.A. N.A. 64.9
Protein Similarity: 100 100 85.8 99.3 N.A. 98.1 98.4 N.A. 80.7 50 80.3 90.4 N.A. 51 N.A. N.A. 79.7
P-Site Identity: 100 100 100 86.6 N.A. 86.6 86.6 N.A. 80 13.3 40 60 N.A. 13.3 N.A. N.A. 13.3
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 93.3 26.6 73.3 66.6 N.A. 33.3 N.A. N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. 31.3 49.3 N.A.
Protein Similarity: N.A. N.A. N.A. 50.8 67.4 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 36 0 0 0 15 0 0 15 0 15 % A
% Cys: 0 0 0 0 8 0 0 0 0 0 15 0 0 0 0 % C
% Asp: 8 8 0 8 0 0 15 8 0 0 0 0 65 0 0 % D
% Glu: 8 0 0 8 8 0 0 0 0 0 0 8 8 8 0 % E
% Phe: 0 0 0 0 0 0 0 0 8 0 0 0 0 8 0 % F
% Gly: 8 65 15 0 15 0 0 0 0 0 0 0 8 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 0 0 8 0 0 0 0 8 0 0 8 % I
% Lys: 58 0 0 0 0 0 0 0 8 0 8 8 0 0 0 % K
% Leu: 0 0 0 0 50 0 65 0 15 0 0 15 0 58 0 % L
% Met: 0 0 0 8 8 0 0 0 8 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 0 8 15 8 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 29 0 0 8 0 0 0 0 0 0 % P
% Gln: 8 0 50 0 0 0 0 0 50 72 65 0 0 0 0 % Q
% Arg: 0 0 15 0 0 8 0 0 0 15 0 58 0 0 8 % R
% Ser: 0 0 8 15 0 0 8 8 0 0 8 0 8 0 8 % S
% Thr: 8 0 0 65 0 29 0 72 0 0 8 0 0 0 0 % T
% Val: 0 0 8 0 15 0 0 0 0 0 0 0 0 22 0 % V
% Trp: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 15 0 0 0 0 0 0 0 0 0 8 0 0 65 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _