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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP2C1
All Species:
27.27
Human Site:
Y452
Identified Species:
46.15
UniProt:
P98194
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P98194
NP_001001485.1
919
100577
Y452
D
Y
I
R
K
A
E
Y
P
F
S
S
E
Q
K
Chimpanzee
Pan troglodytes
XP_001146321
919
100531
Y452
D
Y
I
R
K
A
E
Y
P
F
S
S
E
Q
K
Rhesus Macaque
Macaca mulatta
XP_001113277
1062
115777
Y575
D
Y
I
R
K
T
E
Y
P
F
S
S
E
Q
K
Dog
Lupus familis
XP_863679
919
100526
Y452
D
Y
V
R
K
A
E
Y
P
F
S
S
E
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
Q80XR2
918
100283
Y451
D
Y
I
R
K
A
E
Y
P
F
S
S
E
Q
K
Rat
Rattus norvegicus
Q64566
919
100482
Y452
D
Y
I
R
K
A
E
Y
P
F
S
S
E
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514390
1116
121140
Y651
D
Y
I
R
K
A
E
Y
P
F
S
S
E
Q
K
Chicken
Gallus gallus
Q9YGL9
1042
115411
S507
P
T
G
P
G
H
N
S
A
G
S
K
M
F
V
Frog
Xenopus laevis
NP_001089971
916
100146
P453
Y
I
R
K
K
E
I
P
F
S
S
E
Q
R
W
Zebra Danio
Brachydanio rerio
XP_695172
925
101428
I459
E
F
V
R
L
E
E
I
P
F
T
S
E
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P22700
1020
111683
G507
P
L
K
A
S
R
L
G
T
G
P
K
L
F
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001028821
912
100593
E447
S
E
I
P
F
S
S
E
T
K
W
M
A
V
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92939
1061
116347
N539
L
V
K
G
A
V
E
N
V
L
E
R
S
T
H
Baker's Yeast
Sacchar. cerevisiae
P13586
950
104552
I488
R
K
L
M
A
T
K
I
L
N
P
V
D
N
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
85.5
98.4
N.A.
96.5
97
N.A.
78.8
32.6
66.3
81
N.A.
32
N.A.
N.A.
64.9
Protein Similarity:
100
100
85.8
99.3
N.A.
98.1
98.4
N.A.
80.7
50
80.3
90.4
N.A.
51
N.A.
N.A.
79.7
P-Site Identity:
100
100
93.3
93.3
N.A.
100
100
N.A.
100
6.6
13.3
53.3
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
100
93.3
100
N.A.
100
100
N.A.
100
6.6
33.3
80
N.A.
0
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.3
49.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.8
67.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
15
43
0
0
8
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
50
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% D
% Glu:
8
8
0
0
0
15
65
8
0
0
8
8
58
0
0
% E
% Phe:
0
8
0
0
8
0
0
0
8
58
0
0
0
15
0
% F
% Gly:
0
0
8
8
8
0
0
8
0
15
0
0
0
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
8
50
0
0
0
8
15
0
0
0
0
0
0
0
% I
% Lys:
0
8
15
8
58
0
8
0
0
8
0
15
0
0
65
% K
% Leu:
8
8
8
0
8
0
8
0
8
8
0
0
8
0
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
8
8
0
0
% M
% Asn:
0
0
0
0
0
0
8
8
0
8
0
0
0
8
0
% N
% Pro:
15
0
0
15
0
0
0
8
58
0
15
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
8
58
0
% Q
% Arg:
8
0
8
58
0
8
0
0
0
0
0
8
0
8
8
% R
% Ser:
8
0
0
0
8
8
8
8
0
8
65
58
8
0
0
% S
% Thr:
0
8
0
0
0
15
0
0
15
0
8
0
0
8
0
% T
% Val:
0
8
15
0
0
8
0
0
8
0
0
8
0
8
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% W
% Tyr:
8
50
0
0
0
0
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _