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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP2C1
All Species:
36.97
Human Site:
Y587
Identified Species:
62.56
UniProt:
P98194
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P98194
NP_001001485.1
919
100577
Y587
I
A
S
R
L
G
L
Y
S
K
T
S
Q
S
V
Chimpanzee
Pan troglodytes
XP_001146321
919
100531
Y587
I
A
S
R
L
G
L
Y
S
K
T
S
Q
S
V
Rhesus Macaque
Macaca mulatta
XP_001113277
1062
115777
Y710
I
A
S
R
L
G
L
Y
S
K
T
S
Q
S
V
Dog
Lupus familis
XP_863679
919
100526
Y587
I
A
S
R
L
G
L
Y
S
K
T
S
Q
S
V
Cat
Felis silvestris
Mouse
Mus musculus
Q80XR2
918
100283
Y586
I
A
S
R
L
G
L
Y
S
K
T
S
Q
S
V
Rat
Rattus norvegicus
Q64566
919
100482
Y587
I
A
S
R
L
G
L
Y
S
K
T
S
Q
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514390
1116
121140
Y786
I
A
S
R
L
G
L
Y
S
K
N
S
Q
S
V
Chicken
Gallus gallus
Q9YGL9
1042
115411
F642
I
C
R
R
I
G
I
F
T
E
S
E
D
V
A
Frog
Xenopus laevis
NP_001089971
916
100146
S588
I
G
R
S
I
G
L
S
N
G
H
L
K
A
I
Zebra Danio
Brachydanio rerio
XP_695172
925
101428
Y594
I
A
S
R
L
G
L
Y
T
K
G
S
Q
C
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P22700
1020
111683
F642
I
C
R
R
I
G
V
F
A
E
D
E
D
T
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001028821
912
100593
Y582
V
G
S
R
L
G
L
Y
A
K
G
S
T
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92939
1061
116347
E674
I
G
V
F
E
A
D
E
D
I
S
S
R
S
L
Baker's Yeast
Sacchar. cerevisiae
P13586
950
104552
I623
K
Q
I
G
I
P
V
I
D
P
K
L
S
V
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
85.5
98.4
N.A.
96.5
97
N.A.
78.8
32.6
66.3
81
N.A.
32
N.A.
N.A.
64.9
Protein Similarity:
100
100
85.8
99.3
N.A.
98.1
98.4
N.A.
80.7
50
80.3
90.4
N.A.
51
N.A.
N.A.
79.7
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
20
20
73.3
N.A.
20
N.A.
N.A.
60
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
60
53.3
86.6
N.A.
60
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.3
49.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.8
67.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
58
0
0
0
8
0
0
15
0
0
0
0
8
8
% A
% Cys:
0
15
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
0
0
0
8
0
15
0
8
0
15
0
0
% D
% Glu:
0
0
0
0
8
0
0
8
0
15
0
15
0
0
0
% E
% Phe:
0
0
0
8
0
0
0
15
0
0
0
0
0
0
0
% F
% Gly:
0
22
0
8
0
86
0
0
0
8
15
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
86
0
8
0
29
0
8
8
0
8
0
0
0
0
8
% I
% Lys:
8
0
0
0
0
0
0
0
0
65
8
0
8
0
0
% K
% Leu:
0
0
0
0
65
0
72
0
0
0
0
15
0
0
29
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
0
0
58
0
0
% Q
% Arg:
0
0
22
79
0
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
0
0
65
8
0
0
0
8
50
0
15
72
8
65
0
% S
% Thr:
0
0
0
0
0
0
0
0
15
0
43
0
8
8
8
% T
% Val:
8
0
8
0
0
0
15
0
0
0
0
0
0
15
50
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
65
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _